{"id":"W2016016967","doi":"10.1371/journal.pone.0002314","title":"High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; University of Manitoba; National Eye Institute; American Heart Association","keywords":"Tetraspanin; CD81; Affinity chromatography; Membrane protein; Cell biology; Chemistry; Protein expression; Molecular biology; Biology; Membrane; Biochemistry; Virology; Cell; Gene; Enzyme; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237913,0.0002332183,0.0003239358,0.0002373187,0.0002084029,0.0003351446,0.0002555979,0.0003695702,0.0004627282],"category_scores_gemma":[0.0002351845,0.0001258341,0.0002637036,0.0002941024,0.0001484776,0.0002288599,0.0002798807,0.0005496049,0.0008215327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004374599,"about_ca_system_score_gemma":0.0001849134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005207657,"about_ca_topic_score_gemma":0.0007445606,"domain_scores_codex":[0.9997682,0.00003756026,0.00002707354,0.00004595975,0.00008280016,0.00003840604],"domain_scores_gemma":[0.9998852,0.00002495504,0.00001377664,0.00002339944,0.0000350271,0.00001750626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000856559,0.00001127682,0.00006804559,0.00001452917,0.000001894739,0.00001763258,0.000009050587,0.00004655843,0.9991598,0.00004211257,0.00003113456,0.0005893937],"study_design_scores_gemma":[0.000005457943,0.00005578151,0.001635102,0.000002719809,0.000007825289,0.0002048731,0.00001747666,0.001237071,0.9942529,0.0000484403,0.00252812,0.000004251347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607683,0.002036038,0.03390471,0.0002738807,0.00004427115,0.0001553026,0.001177227,0.0001671946,0.001473043],"genre_scores_gemma":[0.9511021,0.00228784,0.03736688,0.0002499686,0.00002920842,0.0001736832,0.004522258,0.00009927296,0.004168712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005207657,"threshold_uncertainty_score":0.003173947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1189880675581867,"score_gpt":0.2687934906183412,"score_spread":0.1498054230601545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}