{"id":"W2016055585","doi":"10.1016/j.peptides.2010.04.018","title":"Synthesis and biological evaluation of novel peripherally active morphiceptin analogs","year":2010,"lang":"en","type":"article","venue":"Peptides","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biological activity; Chemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000243498,0.0001128667,0.0001740802,0.00004399969,0.00007997052,0.00001779272,0.0001492181,0.00006308292,0.0002310991],"category_scores_gemma":[0.001816435,0.00008513999,0.00004912648,0.0001076439,0.0003027326,0.000110639,0.00008121741,0.0001694359,0.00001281389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006318205,"about_ca_system_score_gemma":0.0000269371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003025468,"about_ca_topic_score_gemma":0.00001856551,"domain_scores_codex":[0.9990235,0.000113064,0.0001606238,0.0003450751,0.0001920817,0.0001656826],"domain_scores_gemma":[0.9992481,0.0003552179,0.0001062362,0.0001495801,0.00008713414,0.00005374133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004603234,0.00009118399,0.00054466,0.000004611341,0.000002917316,0.000001015404,0.0000667361,0.00001598959,0.9818782,0.001728553,0.00002299117,0.01559714],"study_design_scores_gemma":[0.0003264341,0.0001943497,0.125974,0.00001115162,0.00002249395,0.00001836917,0.00008824583,0.002270079,0.869489,0.001112513,0.0003519314,0.0001414616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972525,0.000005566418,0.000006990721,0.0001070138,0.00008537152,0.000141804,0.00002454901,0.000026882,0.002349347],"genre_scores_gemma":[0.9991385,0.00002644548,0.0005020102,0.0002014627,0.00007537239,0.00002251985,8.329581e-7,0.000009633261,0.0000232722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1254294,"threshold_uncertainty_score":0.3471908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1027632431980741,"score_gpt":0.3153453691533328,"score_spread":0.2125821259552588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}