{"id":"W2016174853","doi":"10.1016/j.bbrc.2006.05.142","title":"Regulation of human tyrosine hydroxylase gene by neuron-restrictive silencer factor","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Ministry of Education and Human Resources Development; Korea Science and Engineering Foundation; Ministry of Science and Technology, Croatia; Ministry of Science and Technology","keywords":"Repressor; Transcription factor; Tyrosine hydroxylase; Biology; Trichostatin A; Gene silencing; Promoter; Neuron; Molecular biology; Cell biology; Gene; Gene expression; Histone deacetylase; Histone; Genetics; Neuroscience; Dopamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805191,0.0003589891,0.0002310264,0.0002651077,0.0002140853,0.0003452135,0.0002749762,0.0002505064,0.001485374],"category_scores_gemma":[0.000207217,0.0001455573,0.0002984002,0.00008165548,0.0003845153,0.0001496228,0.0002529178,0.0005093371,0.0005096049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006327716,"about_ca_system_score_gemma":0.0002138072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519359,"about_ca_topic_score_gemma":0.002435547,"domain_scores_codex":[0.9998198,0.00003657849,0.00001647622,0.00004884316,0.00003705964,0.00004126444],"domain_scores_gemma":[0.9998066,0.00008206023,0.00003154966,0.00003199702,0.00001379756,0.00003394683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008239262,0.00001404102,0.0001001524,0.000008598833,0.000003350847,0.00005182437,0.00001805977,0.00004441055,0.9987411,0.0003373854,0.00004311249,0.000555573],"study_design_scores_gemma":[0.00001697873,0.00008112896,0.002044248,0.000003556072,0.000008194805,0.0001861793,0.00003428262,0.001665506,0.9942642,0.0001004759,0.001591038,0.000004330177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991205,0.001513794,0.004624318,0.0001596305,0.00006504189,0.00001846593,0.0004176345,0.0001450655,0.001851094],"genre_scores_gemma":[0.9967392,0.0001965656,0.001109414,0.00004128428,0.000008106649,0.00001125311,0.0003996993,0.00003605188,0.001458389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519359,"threshold_uncertainty_score":0.00496906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08883612764006586,"score_gpt":0.3596341020956538,"score_spread":0.2707979744555879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}