{"id":"W2016191221","doi":"10.3390/cancers6031408","title":"STAT3 in Cancer—Friend or Foe?","year":2014,"lang":"en","type":"article","venue":"Cancers","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Suppressor; Carcinogenesis; Cancer; Context (archaeology); STAT3; Cancer research; Biology; Cancer cell; Phenotype; Function (biology); Tumor initiation; Computational biology; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006587054,0.00007087245,0.0001485702,0.00007428919,0.00002821841,0.000007919406,0.00003834246,0.00003009264,0.001560254],"category_scores_gemma":[0.00007640543,0.00005460071,0.00003645182,0.0001630721,0.00002976298,0.00004536511,0.000009071535,0.0001300092,0.00002641835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007559296,"about_ca_system_score_gemma":0.0004778039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00286879,"about_ca_topic_score_gemma":0.00250939,"domain_scores_codex":[0.9994553,0.00001189098,0.0001310549,0.0001460059,0.00009012385,0.000165655],"domain_scores_gemma":[0.9996722,0.00003759193,0.00003377979,0.000136784,0.00003714631,0.00008245563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004562499,0.00029424,0.06710012,0.0007838494,0.0003552857,0.0002833002,0.008496244,0.0146991,0.2841108,0.007369548,0.2748271,0.3371179],"study_design_scores_gemma":[0.001865651,0.0004543024,0.005814337,0.0003626597,0.00003650128,0.00002085268,0.000412972,0.005364379,0.02232879,0.000075136,0.9631097,0.000154732],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960768,0.0002943168,0.0005600491,0.001243601,0.001018507,0.0002372747,0.00002780985,0.00006713023,0.03578335],"genre_scores_gemma":[0.9955472,0.0001028695,0.0001560868,0.0009676274,0.0002910688,0.00005102466,0.000006806167,0.00001393904,0.002863319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6882825,"threshold_uncertainty_score":0.9993525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0437605484237067,"score_gpt":0.3472010045959292,"score_spread":0.3034404561722225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}