{"id":"W2016296136","doi":"10.1258/0004563001899339","title":"Non-fasting reference intervals for the Abbott IMx <sup>TM</sup> homocysteine and AxSYM <sup>TM</sup> plasma folate assays: influence of the methylenetetrahydrofolate reductase 677 C→T mutation on homocysteine","year":2000,"lang":"en","type":"article","venue":"Annals of Clinical Biochemistry International Journal of Laboratory Medicine","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Abbott Diagnostics","keywords":"Methylenetetrahydrofolate reductase; Homocysteine; Internal medicine; Hyperhomocysteinemia; Endocrinology; Genotype; Chemistry; Reductase; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003713854,0.0007931155,0.000639835,0.001689283,0.0005062862,0.0008489483,0.0009954632,0.0007979745,0.002120043],"category_scores_gemma":[0.00788545,0.0003093079,0.0004198778,0.00174212,0.0002740554,0.0002148808,0.0003914045,0.0007271671,0.001879985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004956097,"about_ca_system_score_gemma":0.0005394298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0037892,"about_ca_topic_score_gemma":0.004788182,"domain_scores_codex":[0.9931253,0.002898915,0.0007619622,0.0008905182,0.002116939,0.0002063534],"domain_scores_gemma":[0.9927167,0.001958312,0.001477166,0.0009851974,0.002567222,0.0002955349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01067733,0.0008533406,0.4547003,0.001437455,0.000668946,0.001032239,0.001937394,0.001230946,0.1475246,0.002590363,0.03436503,0.3429821],"study_design_scores_gemma":[0.0003183824,0.003337259,0.8602953,0.0004644954,0.000481029,0.003765472,0.0004439437,0.003902507,0.0702087,0.0009666605,0.05570739,0.0001088577],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8224936,0.03707266,0.08429786,0.001153018,0.001417483,0.0006746746,0.01571779,0.003294387,0.03387851],"genre_scores_gemma":[0.8425795,0.003898531,0.1159138,0.001243284,0.000261839,0.001881106,0.02055539,0.0005445434,0.01312206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0037892,"threshold_uncertainty_score":0.01964098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07801043742402206,"score_gpt":0.4225323982003207,"score_spread":0.3445219607762987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}