{"id":"W2016366885","doi":"10.1038/nature09584","title":"mTORC1 controls fasting-induced ketogenesis and its modulation by ageing","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":656,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; American Diabetes Association; Howard Hughes Medical Institute","keywords":"Ketogenesis; mTORC1; TSC1; Energy homeostasis; Mechanistic target of rapamycin; PI3K/AKT/mTOR pathway; Biology; Activator (genetics); Repressor; Ketone bodies; Endocrinology; Cell biology; Internal medicine; Receptor; Signal transduction; Transcription factor; Metabolism; Biochemistry; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006669083924658362,"score_gpt":0.2576910491801227,"score_spread":0.2510219652554643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}