{"id":"W2016371380","doi":"10.1038/labinvest.2008.89","title":"Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation","year":2008,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Integrin; Tenascin; Cell adhesion; Cell adhesion molecule; Extracellular matrix; Medulloblastoma; Cell biology; Cancer research; Neural cell adhesion molecule; Glioma; Biology; Immunology; Fibronectin; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001253373,0.0003898816,0.0001326267,0.000439467,0.000412941,0.0004770511,0.000176268,0.0002021714,0.002172696],"category_scores_gemma":[0.0001620322,0.0001274494,0.0002383214,0.0002449102,0.0001588852,0.0002686846,0.0002507224,0.000503896,0.0004270752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006210885,"about_ca_system_score_gemma":0.0002957698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00534945,"about_ca_topic_score_gemma":0.008765985,"domain_scores_codex":[0.9997861,0.00003723648,0.000008443416,0.00001467901,0.00005480925,0.0000987295],"domain_scores_gemma":[0.9999334,0.00001295036,0.00001718418,0.000005966681,0.00001151908,0.00001902333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001638089,0.00002550013,0.00103097,0.00003426339,0.000009432826,0.0001446321,0.00006751957,0.00007154486,0.9947108,0.0005890934,0.0001780272,0.002974384],"study_design_scores_gemma":[0.00003920364,0.0002460399,0.03651686,0.00001575873,0.00004301179,0.0007256448,0.0003774586,0.001662755,0.9525383,0.0002510836,0.007576414,0.000007591612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990445,0.002376464,0.001516844,0.0001484776,0.00001782213,0.00003875912,0.0002889444,0.00003129403,0.005136474],"genre_scores_gemma":[0.9931449,0.0011762,0.0009897979,0.00003210712,0.00001006281,0.0000332585,0.000320829,0.000006732484,0.004286102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00534945,"threshold_uncertainty_score":0.01063663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02706922129570782,"score_gpt":0.2441422255082792,"score_spread":0.2170730042125714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}