{"id":"W2016433770","doi":"10.1006/bbrc.2001.5673","title":"Hormone Response of Rodent Phenylalanine Hydroxylase Requires HNF1 and the Glucocorticoid Receptor","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministère de l'Enseignement Supérieur, de la Recherche, de la Science et de la Technologie; Association pour la Recherche sur le Cancer","keywords":"Glucocorticoid receptor; Hormone response element; Glucocorticoid; Phenylalanine hydroxylase; Transcription factor; Response element; Enhancer; Protein kinase A; Biology; Serine; Nuclear receptor; Chemistry; Kinase; Endocrinology; Biochemistry; Phosphorylation; Gene; Phenylalanine; Gene expression; Promoter; Genetics; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001485262,0.0002658625,0.0001774128,0.0002552825,0.0001983648,0.0002417057,0.0001806646,0.0002596289,0.001226222],"category_scores_gemma":[0.0002732969,0.0001916287,0.000269256,0.0001138652,0.0002531655,0.000152428,0.0001597358,0.0003036605,0.0003774423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007190491,"about_ca_system_score_gemma":0.0001978796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002711504,"about_ca_topic_score_gemma":0.004677227,"domain_scores_codex":[0.9998496,0.0000242723,0.000006443122,0.00003153664,0.00002615372,0.00006205838],"domain_scores_gemma":[0.9997655,0.00003605452,0.00005736134,0.00003489562,0.00003123227,0.00007506457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002376874,0.000009716417,0.0003629264,0.000008814803,0.000003219167,0.00005576735,0.000009110691,0.00003116274,0.9982097,0.0001116423,0.00006351907,0.0008968289],"study_design_scores_gemma":[0.00002857212,0.0002027866,0.03211493,0.000005762407,0.00001113412,0.0004668463,0.00005347692,0.0006002405,0.9636319,0.0001743459,0.002698783,0.00001117014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942383,0.002037344,0.001585348,0.000265571,0.0000372889,0.000009807613,0.000296397,0.0001214838,0.001408411],"genre_scores_gemma":[0.9944853,0.0004645632,0.0009818047,0.00007149297,0.00000912392,0.000009647318,0.0007465759,0.00002414282,0.003207291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002711504,"threshold_uncertainty_score":0.005391359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03598607645226701,"score_gpt":0.3344469115996734,"score_spread":0.2984608351474064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}