{"id":"W2016460575","doi":"10.1002/ajmg.b.30992","title":"CAG‐repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches","year":2009,"lang":"en","type":"review","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":364,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke","keywords":"Psychology; Disease; Perspective (graphical); Survival analysis; Medicine; Computer science; Internal medicine; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001692862,0.0006294851,0.003176355,0.0004413013,0.00008374554,0.00005022161,0.001098041,0.0001035814,0.00001583032],"category_scores_gemma":[0.003689035,0.0004275887,0.0003173728,0.00127898,0.001794318,0.00002840658,0.0003439408,0.0009271217,8.79839e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002024508,"about_ca_system_score_gemma":0.0007954066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001138357,"about_ca_topic_score_gemma":0.000007273051,"domain_scores_codex":[0.9882667,0.005260637,0.003084094,0.0007919702,0.00217094,0.0004256653],"domain_scores_gemma":[0.9935405,0.002032621,0.002909183,0.0007624633,0.0001496776,0.0006056129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002203281,0.002332515,0.002451351,0.01043822,0.0001341985,0.0001953413,0.0003511373,0.0001580235,0.000008781921,0.0000910321,0.0003355423,0.9832835],"study_design_scores_gemma":[0.06222064,0.09106591,0.1620532,0.1055849,0.1517816,0.006744,0.004078406,0.003882511,0.0008578772,0.003254711,0.3953032,0.01317294],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1731666,0.8245126,0.000119215,0.0003322692,0.0002166591,0.001546686,0.00008769846,0.000005205451,0.00001303426],"genre_scores_gemma":[0.087426,0.9114547,0.0004385175,0.0004514359,0.000124669,0.0000275087,0.00000891118,0.0000630711,0.000005241731],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9701106,"threshold_uncertainty_score":0.9998176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06078828323692004,"score_gpt":0.3405133718963326,"score_spread":0.2797250886594126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}