{"id":"W2016471840","doi":"10.1016/s0027-5107(02)00285-3","title":"Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue™ rat tongue epithelial cells and fibroblasts","year":2003,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada; University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"4-Nitroquinoline 1-oxide; Carcinogen; Glutathione; Fibroblast; Cell culture; Genotoxicity; Molecular biology; Cytotoxic T cell; Mutagenesis; Cell; In vitro; Biology; Mutagen; Chemistry; Carcinogenesis; Toxicity; Mutant; Biochemistry; Genetics; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005624989,0.0002010147,0.0002470969,0.0001364215,0.0001263911,0.0000243383,0.0001747215,0.0001586447,0.00002349574],"category_scores_gemma":[0.00006898207,0.0001634226,0.0001265077,0.0002490542,0.0002801753,0.00001069408,0.0001365825,0.0001331031,0.000001074595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002084059,"about_ca_system_score_gemma":0.0001023518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00043975,"about_ca_topic_score_gemma":0.0002119043,"domain_scores_codex":[0.9980189,0.0004905751,0.000357016,0.0003987826,0.0003993375,0.0003353989],"domain_scores_gemma":[0.9993647,0.00003082057,0.00008951939,0.000268469,0.0001279264,0.0001186196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001447192,0.0001129625,0.0003664821,0.00008089749,0.00004720375,0.00001878462,0.0002166066,0.0001932779,0.9969115,0.00149434,0.00001956617,0.000393723],"study_design_scores_gemma":[0.001255743,0.0004103229,0.001567412,0.00003228412,0.00003006588,0.00003047214,0.000729527,0.00006553251,0.9942036,0.001293984,0.0002185256,0.000162543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953319,0.0009071626,0.002854315,0.0001179576,0.00008022205,0.0005210306,0.0001357032,0.000004371652,0.00004736547],"genre_scores_gemma":[0.9976101,0.0001963401,0.001861805,0.0001159245,0.00001033923,0.00003212781,0.00003478037,0.00002580854,0.0001127777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002707848,"threshold_uncertainty_score":0.6664181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01682179845769661,"score_gpt":0.2698799897466921,"score_spread":0.2530581912889955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}