{"id":"W2016475405","doi":"10.1159/000139520","title":"Effects of Aminoguanidine on Adhesion Molecule Expression of Human Endothelial Cells","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"AGE-WELL","keywords":"Downregulation and upregulation; Glycation; Umbilical vein; Cell adhesion molecule; Fibronectin; Chemistry; Cell adhesion; Human umbilical vein endothelial cell; Adhesion; Intercellular Adhesion Molecule-1; ICAM-1; Extracellular matrix; In vitro; Endothelium; Molecular biology; Immunology; Biochemistry; Endocrinology; Cell; Medicine; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007352729,0.00009904914,0.0001524619,0.00006816121,0.00005361364,5.709404e-7,0.0001682562,0.0000778537,0.00007600676],"category_scores_gemma":[0.00005306401,0.0000918453,0.00005046706,0.00007278316,0.000144741,0.000002636084,0.00009360288,0.00008727185,0.000009647512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008698775,"about_ca_system_score_gemma":0.00003903074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004444598,"about_ca_topic_score_gemma":2.040456e-7,"domain_scores_codex":[0.9991265,0.0001372651,0.0001844288,0.0002469941,0.0001363204,0.0001685059],"domain_scores_gemma":[0.9995083,0.00004785618,0.0001154015,0.0001739279,0.0001024791,0.00005201098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002948047,0.0002559794,0.00006958064,0.00008412162,0.00001508069,0.000009079436,0.00004480748,0.00008577199,0.9958504,0.00002038962,0.003052749,0.0002171861],"study_design_scores_gemma":[0.001142125,0.0009330428,0.0003188042,0.000009411925,0.000009705694,0.000004506251,0.000003689127,0.000006015663,0.9939794,0.00001763548,0.003499918,0.00007574479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984183,0.0002942717,0.0002831235,0.00003182419,0.0001708198,0.0002616972,0.00001330013,0.000006676422,0.0005200317],"genre_scores_gemma":[0.9981537,0.0004499943,0.0003266185,0.0001003601,0.000179571,0.00002534161,0.00002708148,0.00001657182,0.0007207572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001871049,"threshold_uncertainty_score":0.3745343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01900703004072551,"score_gpt":0.3323954432856269,"score_spread":0.3133884132449014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}