{"id":"W2016475405","doi":"10.1159/000139520","title":"Effects of Aminoguanidine on Adhesion Molecule Expression of Human Endothelial Cells","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"AGE-WELL","keywords":"Downregulation and upregulation; Glycation; Umbilical vein; Cell adhesion molecule; Fibronectin; Chemistry; Cell adhesion; Human umbilical vein endothelial cell; Adhesion; Intercellular Adhesion Molecule-1; ICAM-1; Extracellular matrix; In vitro; Endothelium; Molecular biology; Immunology; Biochemistry; Endocrinology; Cell; Medicine; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197042,0.0002373165,0.000198511,0.000106109,0.0001093213,0.0001799473,0.0001078084,0.0002563154,0.0007081048],"category_scores_gemma":[0.0002236704,0.00009387517,0.0001638997,0.00009762441,0.0001257931,0.00009802712,0.0001076283,0.0002319295,0.0001223772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001340396,"about_ca_system_score_gemma":0.0000820768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004256952,"about_ca_topic_score_gemma":0.0005919298,"domain_scores_codex":[0.9997846,0.0000938931,0.00001685988,0.00003065025,0.00003699443,0.00003711015],"domain_scores_gemma":[0.9998777,0.0000530108,0.00002028084,0.00001559441,0.0000173867,0.00001603826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002801063,0.00004977898,0.0001564634,0.00003656626,0.000007963262,0.00006320613,0.00001778649,0.00003204332,0.9973403,0.00003343223,0.00002087526,0.001961573],"study_design_scores_gemma":[0.00003649985,0.002163582,0.005056127,0.00000764845,0.00002462471,0.0002500223,0.00002075348,0.0003708841,0.9902501,0.00002436535,0.001791444,0.000003946682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934462,0.004670185,0.0005417088,0.00005393618,0.00004391367,0.00001573547,0.00005243406,0.00001461669,0.001161132],"genre_scores_gemma":[0.9959502,0.001863134,0.00107711,0.0000775748,0.00002963312,0.00002042087,0.0001571581,0.000004162248,0.0008205305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007081048,"threshold_uncertainty_score":0.002368867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01900703004072551,"score_gpt":0.3323954432856269,"score_spread":0.3133884132449014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}