{"id":"W2016518559","doi":"10.1186/bcr2183","title":"Who should participate in clinical trials and who not? Can clinical trials be made more efficient and effective?","year":2008,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre","funders":"","keywords":"Surgical oncology; Clinical trial; Medicine; Medical physics; Alternative medicine; Oncology; Internal medicine; Family medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4067088,0.001623103,0.006690775,0.002938195,0.005830841,0.02114355,0.004804289,0.03880672,0.02290803],"category_scores_gemma":[0.5877529,0.00258033,0.002761962,0.002894317,0.02502273,0.02792764,0.007789579,0.02393934,0.01419596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005332122,"about_ca_system_score_gemma":0.03218511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001985963,"about_ca_topic_score_gemma":0.002597485,"domain_scores_codex":[0.6531087,0.2790924,0.01876099,0.007026318,0.03410582,0.007905863],"domain_scores_gemma":[0.2803568,0.5190344,0.05282591,0.03753388,0.04442254,0.06582649],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.004934505,0.003575462,0.01542437,0.005427392,0.001546354,0.0009734703,0.003126429,0.001498797,0.002129412,0.07019368,0.4424931,0.448677],"study_design_scores_gemma":[0.008837753,0.002072959,0.01662983,0.009871118,0.001133086,0.001200828,0.005337286,0.001902539,0.002275313,0.2874243,0.662532,0.0007828635],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002282514,0.01639511,0.006743225,0.9522178,0.01253911,0.0008179075,0.0001325596,0.0001288235,0.008743016],"genre_scores_gemma":[0.06940852,0.02460006,0.04555421,0.7927019,0.04636832,0.006925059,0.0003332758,0.0003013654,0.01380728],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5932912,"threshold_uncertainty_score":0.7316337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4252190525123311,"score_gpt":0.5813847429662543,"score_spread":0.1561656904539233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}