{"id":"W2016578600","doi":"10.1186/1742-4690-8-s1-a99","title":"HTLV-1 HBZ protein inhibits IRF3-mediated innate immune responses","year":2011,"lang":"en","type":"article","venue":"Retrovirology","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"IRF3; IRF7; Interferon; Interferon regulatory factors; Innate immune system; Immunology; Immune system; Virology; Biology; Transcription factor; Transfection; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004853552,0.0003927044,0.000672885,0.0003249627,0.0003655744,0.000008405731,0.0004180098,0.00077079,0.001620921],"category_scores_gemma":[0.0004699217,0.0003164614,0.0001661256,0.0003009791,0.001017785,0.000101569,0.0003628812,0.0007770556,0.005100935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005390253,"about_ca_system_score_gemma":0.00009081698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004375013,"about_ca_topic_score_gemma":0.00005922014,"domain_scores_codex":[0.9971406,0.0006925619,0.0005933762,0.0005928234,0.00005733362,0.0009233466],"domain_scores_gemma":[0.9988385,0.0001943915,0.0002674595,0.0005406616,0.0001101353,0.00004881174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001716806,0.0002353326,0.01044844,0.00002408101,0.000323221,0.0000592509,0.0009742237,1.381688e-7,0.9816684,0.001940816,0.001225228,0.001384071],"study_design_scores_gemma":[0.004063182,0.002489686,0.1117723,0.00004906268,0.0001211282,0.0002571292,0.0003881967,0.000001274704,0.7829395,0.0008284757,0.09629621,0.0007938393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797421,0.007963146,0.00002918031,0.0005889455,0.001020642,0.0004588135,0.00006092744,0.0003114199,0.009824829],"genre_scores_gemma":[0.9804956,0.0002646364,0.0001381296,0.0003996309,0.00006087638,0.0001007991,0.00007466331,0.00004541804,0.01842027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1987289,"threshold_uncertainty_score":0.9999288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273584321649227,"score_gpt":0.215840606829287,"score_spread":0.1931047636127948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}