{"id":"W2016581293","doi":"10.3389/fgene.2013.00132","title":"Cigarette smoking and DNA methylation","year":2013,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":389,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; University of Toronto; Université de Sherbrooke","keywords":"DNA methylation; Epigenetics; Epigenome; Biology; Genetics; Methylation; Context (archaeology); Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000164923,0.0001175012,0.0001105654,0.00007936761,0.00004401041,0.0000381368,0.0000899569,0.0001668771,0.00001105639],"category_scores_gemma":[0.00004370397,0.0001252815,0.00002841683,0.00008945398,0.00005440975,0.000004348919,0.00006796372,0.00007625523,0.000001687885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001419966,"about_ca_system_score_gemma":0.00001903831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001191411,"about_ca_topic_score_gemma":0.000008883726,"domain_scores_codex":[0.9991775,0.00005329553,0.0001952674,0.0002683364,0.0001098827,0.00019568],"domain_scores_gemma":[0.9996029,0.000006546998,0.00005822782,0.0002149899,0.00005314395,0.00006424468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001323246,0.00003094031,0.325721,0.00002021459,0.0000640454,0.00000114354,0.0001650607,0.0006641549,0.5171028,0.00003382982,0.003428286,0.1527553],"study_design_scores_gemma":[0.0007711151,0.0002021003,0.3211645,0.00001668359,0.00003620135,0.000001623822,0.0001905532,0.004409175,0.6392868,0.005668107,0.02782272,0.0004304223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.95979,0.0125964,0.02607676,0.0001170435,0.0003864862,0.0002126785,0.000002763578,0.000006970472,0.0008109274],"genre_scores_gemma":[0.9848793,0.001771653,0.01283003,0.0001091608,0.000131144,0.00002368094,0.00004357748,0.00002122883,0.0001902919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1523249,"threshold_uncertainty_score":0.5108833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007504875229948939,"score_gpt":0.2253878593880463,"score_spread":0.2178829841580973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}