{"id":"W2016613054","doi":"10.1242/jcs.025957","title":"LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor","year":2009,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"HT1080; CTGF; Fibronectin; Fibrosarcoma; Biology; Molecular biology; Transfection; Connective tissue; Growth factor; Messenger RNA; Cell biology; Cell culture; Gene; Extracellular matrix; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001008783,0.0002008192,0.0002460309,0.0002582517,0.0002291991,0.0001301149,0.0006253314,0.000130375,0.00005226254],"category_scores_gemma":[0.00118083,0.0001765921,0.00008913724,0.0006566137,0.000284241,0.00009513338,0.0000584715,0.0003027784,0.000008028876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001033889,"about_ca_system_score_gemma":0.000393569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005846808,"about_ca_topic_score_gemma":0.000005899547,"domain_scores_codex":[0.9977993,0.0002017458,0.0003997632,0.0003746619,0.0007588325,0.0004656622],"domain_scores_gemma":[0.9982292,0.0001798415,0.0003448564,0.0001761258,0.0007578706,0.0003120773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002016976,0.00009257529,0.001958295,0.000009985476,0.00001053998,0.000009651625,0.0002527757,0.000001977881,0.994123,0.00001521998,0.0002624131,0.003061885],"study_design_scores_gemma":[0.0007121168,0.001628373,0.03294136,0.00002596479,0.000009096754,0.00007988379,0.0001171694,0.0000237959,0.9632728,0.0002060684,0.0007793372,0.0002040062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957491,0.0008937073,0.001160138,0.0005426787,0.0001298017,0.000186778,0.00002252497,0.000009212039,0.001306015],"genre_scores_gemma":[0.9986317,0.0001273231,0.0009147527,0.00007095384,0.0001749732,0.00000119679,0.000008444174,0.00001377075,0.00005686833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03098307,"threshold_uncertainty_score":0.7201218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0162613187742888,"score_gpt":0.2887794629716575,"score_spread":0.2725181441973688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}