{"id":"W2016613547","doi":"10.1038/mtna.2014.2","title":"R88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected Cells","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"","keywords":"Virology; Biology; Viral replication; Cell culture; Viral vector; Virus; Antiviral drug; Vector (molecular biology); Drug resistance; Gene; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002990425,0.0001631631,0.0002661713,0.00006405756,0.00009927379,0.00001186831,0.0002069163,0.0001060403,0.0001345081],"category_scores_gemma":[0.00005939433,0.0001088443,0.00008296077,0.0001335171,0.0003123927,0.00003751875,0.00006014138,0.0001428168,0.00006502831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001674118,"about_ca_system_score_gemma":0.00004189975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003551368,"about_ca_topic_score_gemma":0.00002490667,"domain_scores_codex":[0.9986708,0.000385416,0.0002819895,0.0003572436,0.00007881408,0.0002257979],"domain_scores_gemma":[0.9988823,0.00008419981,0.0001635488,0.0007560397,0.00008566816,0.0000282794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002657577,0.0002200187,0.002836991,0.00001070946,0.0003372432,0.000001566196,0.0006501132,0.000002912833,0.9861303,0.0003430816,0.0002120298,0.008989308],"study_design_scores_gemma":[0.001829485,0.0003435262,0.03393965,0.00002487321,0.00003243266,0.00000172335,0.00004752304,0.000004365919,0.9565857,0.0002145836,0.006878522,0.00009763428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966172,0.001877088,0.0001822258,0.0003583889,0.00003999612,0.0004816051,0.0001761813,0.00003139272,0.000235949],"genre_scores_gemma":[0.9991447,0.0002486625,0.0001219959,0.0001350269,0.00000916662,0.00002531235,0.0001483856,0.00002214239,0.0001445766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03110266,"threshold_uncertainty_score":0.4438543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208827405698145,"score_gpt":0.2402584025263833,"score_spread":0.2281701284694019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}