{"id":"W2016614121","doi":"10.4161/cc.1.6.265","title":"Open Heart Surgery of PI-3 Kinase Signaling","year":2002,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Kinase; Signal transduction; Protein-Serine-Threonine Kinases; Cell biology; Pi; Protein kinase A; Cancer research; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004469787,0.0004706435,0.0005956662,0.0002731429,0.0007078467,0.001000208,0.0003306435,0.006055539,0.008493881],"category_scores_gemma":[0.002235896,0.000212339,0.00066803,0.0001744653,0.0009742708,0.0006819346,0.0003003161,0.007735439,0.003901872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001153472,"about_ca_system_score_gemma":0.0005756373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005203102,"about_ca_topic_score_gemma":0.001729959,"domain_scores_codex":[0.9997377,0.00004885122,0.00002226422,0.00003202858,0.00009554229,0.00006361096],"domain_scores_gemma":[0.9994998,0.0002720274,0.00003963431,0.00003792689,0.00004352969,0.000107101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001623209,0.0002032333,0.00335482,0.0002547815,0.00008448902,0.03003244,0.00008797961,0.0002935528,0.005958539,0.0126242,0.7983348,0.147148],"study_design_scores_gemma":[0.0006473695,0.000497174,0.005792638,0.0002152414,0.00009861265,0.02724214,0.0001169543,0.0008672177,0.004974893,0.01492085,0.9445687,0.00005821094],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01563621,0.03060578,0.003090649,0.8034659,0.05985911,0.00006093035,0.0002102421,0.000412828,0.08665838],"genre_scores_gemma":[0.1645835,0.02411222,0.002045345,0.4903005,0.165732,0.000180938,0.0004134293,0.00008436777,0.1525478],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.008493881,"threshold_uncertainty_score":0.02841485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02670769428141362,"score_gpt":0.2555490412616662,"score_spread":0.2288413469802526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}