{"id":"W2016634375","doi":"10.1016/s0140-6736(15)60297-5","title":"Rare diseases and effective treatments: are we delivering?","year":2015,"lang":"en","type":"article","venue":"The Lancet","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; European union; Medical prescription; Antibiotic resistance; European commission; Rare disease; Family medicine; Intensive care medicine; Pediatrics; Antibiotics; Disease; Pathology; Business; Biology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03330993,0.002223244,0.006717693,0.003250855,0.004140632,0.01429148,0.003291339,0.0237776,0.03815261],"category_scores_gemma":[0.06590866,0.001511215,0.002625772,0.002596626,0.01612894,0.0342108,0.008264665,0.03764241,0.01156544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008731609,"about_ca_system_score_gemma":0.02441945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006525219,"about_ca_topic_score_gemma":0.009757131,"domain_scores_codex":[0.98522,0.004984425,0.001283446,0.001224099,0.005085333,0.002202683],"domain_scores_gemma":[0.8945648,0.065951,0.006217123,0.004308362,0.01594604,0.01301261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003242905,0.0002508808,0.0008994866,0.003391716,0.0002606958,0.0002749631,0.0003675024,0.0004519951,0.000415626,0.09038252,0.652934,0.2500463],"study_design_scores_gemma":[0.0003718072,0.0001839199,0.001386427,0.007697782,0.0002564956,0.0004067725,0.001186988,0.000334518,0.0001984477,0.1607636,0.8270481,0.0001652264],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001979392,0.3341736,0.0008690274,0.6363619,0.02305779,0.0000146624,0.00009343382,0.0000681092,0.005163443],"genre_scores_gemma":[0.0115126,0.5353881,0.003282675,0.3068935,0.1368359,0.0001152145,0.0002177204,0.00009449848,0.00565972],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03815261,"threshold_uncertainty_score":0.1761618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03824806269975924,"score_gpt":0.2844943919378012,"score_spread":0.246246329238042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}