{"id":"W2016685424","doi":"10.1039/c1cc16409k","title":"Highly enantioselective Mukaiyama aldol reaction in aqueous conditions using a chiral iron(<scp>ii</scp>) bipyridine catalyst","year":2011,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Aldol reaction; Enantioselective synthesis; Chemistry; Catalysis; Enol; Silylation; Bipyridine; Aqueous solution; Organic chemistry; Ligand (biochemistry); Combinatorial chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003154144,0.0003485438,0.0004127176,0.0001254926,0.0003963324,0.00002949772,0.001324851,0.0003931182,0.000165965],"category_scores_gemma":[0.002280307,0.000394609,0.0001696733,0.0006607603,0.0005374457,0.0002052797,0.000790599,0.0009596844,0.00004184009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006042479,"about_ca_system_score_gemma":0.0001798271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005466338,"about_ca_topic_score_gemma":0.00004918434,"domain_scores_codex":[0.9979368,0.0001173705,0.0006680982,0.0005268257,0.000235304,0.0005155468],"domain_scores_gemma":[0.9956209,0.001232113,0.0003109071,0.002476912,0.0001547945,0.000204354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006860927,0.0007268128,0.0005178378,0.00004228329,0.00005042793,0.000003864593,0.00173666,8.221763e-7,0.9957075,0.000384668,0.0001706765,0.0006516492],"study_design_scores_gemma":[0.0004645919,0.00001097333,0.0003689709,0.0001664137,0.0001195586,0.0001587149,0.0009871501,0.0007487611,0.9927601,0.00140981,0.002591429,0.0002135044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397762,0.0005404647,0.0001118304,0.0001768461,0.00006295522,0.0001573853,0.0001033885,0.0002639157,0.05880699],"genre_scores_gemma":[0.9845073,0.00009055896,0.01398441,0.0000445431,0.0001114277,0.000124278,0.0003280513,0.0000749444,0.0007345476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05807244,"threshold_uncertainty_score":0.9998506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06296750803957474,"score_gpt":0.3080523418195881,"score_spread":0.2450848337800133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}