{"id":"W2016827479","doi":"10.3747/co.v17i4.700","title":"Optimizing the Management of her2-Positive Early Breast Cancer: The Clinical Reality","year":2010,"lang":"en","type":"article","venue":"Current Oncology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Toronto; Université de Sherbrooke; University of Ottawa; Centre hospitalier universitaire de Québec; Hôpital du Saint-Sacrement; Health Sciences Centre; Ottawa Hospital; Santé Montérégie; University of Alberta; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Trastuzumab; Medicine; Breast cancer; Oncology; Internal medicine; Anthracycline; Population; Stage (stratigraphy); Disease; Clinical trial; Cancer; Adjuvant; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002196732,0.0001253824,0.0003583078,0.00003534686,0.000125107,0.00001303851,0.0004332726,0.0001334124,0.0004055958],"category_scores_gemma":[0.00005519195,0.00006754606,0.000154976,0.0002205459,0.0008927931,0.00002797359,0.0002860506,0.001417799,0.00003545031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776195,"about_ca_system_score_gemma":0.0004224083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005027926,"about_ca_topic_score_gemma":0.0003059295,"domain_scores_codex":[0.9980343,0.0004129585,0.0004783135,0.0003097334,0.0004013013,0.0003633968],"domain_scores_gemma":[0.9982646,0.0004823098,0.0001741008,0.0006624716,0.0002725329,0.0001440235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006018999,0.0008808442,0.08859527,0.0002286747,0.0003519766,0.00004251944,0.001066195,0.000005315863,0.0001671142,0.002850931,0.01518885,0.8900204],"study_design_scores_gemma":[0.001543809,0.0005386497,0.7299073,0.0002478307,0.0002665545,0.00006857669,0.0004610777,0.0002017782,0.0001618005,0.000181117,0.2663225,0.00009899169],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8931838,0.001821852,0.0002415765,0.07226223,0.006107311,0.002230204,0.0001434582,0.00005618874,0.02395343],"genre_scores_gemma":[0.9947962,0.002882015,0.0004083152,0.000330458,0.001075374,0.0002221176,0.000009023093,0.00002109948,0.0002554091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8899214,"threshold_uncertainty_score":0.6159711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2447587637129754,"score_gpt":0.5587603142850097,"score_spread":0.3140015505720343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}