{"id":"W2016836075","doi":"10.1016/j.vaccine.2015.02.055","title":"Outer membrane proteins preferentially load MHC class II peptides: Implications for a Chlamydia trachomatis T cell vaccine","year":2015,"lang":"en","type":"article","venue":"Vaccine","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Centre for Disease Control; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Health Canada; National Institutes of Health; Canada Research Chairs","keywords":"Chlamydia trachomatis; Biology; Epitope; Antigen; MHC class I; MHC class II; Virology; Major histocompatibility complex; Bacterial outer membrane; T cell; Microbiology; Chlamydiaceae; Molecular biology; Immune system; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003303098,0.0003766521,0.0001927234,0.0001434274,0.0002854749,0.0007567411,0.0002777435,0.000654082,0.003964345],"category_scores_gemma":[0.0004061789,0.000135041,0.0001578524,0.0001173283,0.0003481723,0.0004932372,0.0002739423,0.0007222518,0.0006825543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003837163,"about_ca_system_score_gemma":0.0004466293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008335897,"about_ca_topic_score_gemma":0.0006343008,"domain_scores_codex":[0.9998473,0.00003527753,0.000004859368,0.00002415722,0.00001933776,0.00006908079],"domain_scores_gemma":[0.999838,0.0000372829,0.00003059948,0.0000150844,0.00003284417,0.00004611184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005344264,0.0002019015,0.002324304,0.0001072294,0.00001402359,0.0001721793,0.00005544628,0.0002549884,0.978249,0.001745763,0.001128681,0.01521214],"study_design_scores_gemma":[0.0003985767,0.005374134,0.05031585,0.0001392229,0.0001855515,0.00227652,0.0007681888,0.006968156,0.8765579,0.004667646,0.05231079,0.00003753053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756575,0.007235412,0.005430957,0.00366339,0.0004204865,0.00007047887,0.0001553077,0.00008385135,0.007282604],"genre_scores_gemma":[0.993277,0.002021973,0.001522844,0.0005110326,0.0001110634,0.00002263524,0.0001017357,0.00001613543,0.002415543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003964345,"threshold_uncertainty_score":0.01326203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03950231541175601,"score_gpt":0.3005460496239941,"score_spread":0.261043734212238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}