{"id":"W2016848711","doi":"10.1046/j.1365-2567.2000.00981.x","title":"T‐cell tolerance induction is normal in the (NZB × NZW)F<sub>1</sub> murine model of systemic lupus erythematosus","year":2000,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"Arthritis Society","keywords":"Biology; Immune tolerance; Immunology; T cell; Clonal anergy; Transgene; Clonal deletion; Autoantibody; Peripheral tolerance; Major histocompatibility complex; Autoimmunity; Antigen; Genetically modified mouse; Antibody; Immune system; T-cell receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000400585,0.0004121553,0.0007433199,0.0002812087,0.0002159423,0.00001268438,0.0008546392,0.0008475895,0.0005855351],"category_scores_gemma":[0.00001895377,0.0003281241,0.0002022193,0.000391434,0.0007361075,0.0001801795,0.00012557,0.001013209,0.001335468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007214366,"about_ca_system_score_gemma":0.0001170722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002103875,"about_ca_topic_score_gemma":0.00003550148,"domain_scores_codex":[0.9970534,0.0005559316,0.0009269736,0.0005569792,0.00007253585,0.0008341245],"domain_scores_gemma":[0.9984706,0.0001717445,0.0003193592,0.0009265564,0.00009594286,0.00001580495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006524587,0.0005196228,0.0007502468,0.00005754816,0.000138035,0.00001619383,0.003601182,0.0005278506,0.9854876,0.000387071,0.001462944,0.00639922],"study_design_scores_gemma":[0.004355511,0.0004931123,0.0005500799,0.0001016738,0.00007286413,0.004030676,0.001259746,0.0001610163,0.9847844,0.0005343094,0.003234533,0.0004220408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772089,0.01786829,0.00006037816,0.0003938161,0.001302518,0.0004653725,0.00003657068,0.00008417242,0.002579991],"genre_scores_gemma":[0.9937629,0.002785297,0.00003345933,0.0003252738,0.00004631107,0.0001033316,0.00006388583,0.0000369577,0.002842603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01655399,"threshold_uncertainty_score":0.9999171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009515097455774587,"score_gpt":0.1981912436251732,"score_spread":0.1886761461693987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}