{"id":"W2016961199","doi":"10.1139/y10-001","title":"Oxidative stress and aging: Is methylglyoxal the hidden enemy?This review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.","year":2010,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Methylglyoxal; Oxidative stress; Glycation; Reactive oxygen species; Oxidative phosphorylation; Chemistry; Biochemistry; Mitochondrion; Diabetes mellitus; Ageing; Internal medicine; Endocrinology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004627218,0.0008072435,0.001730538,0.001441883,0.0004941478,0.001080462,0.0008227422,0.001625777,0.004201456],"category_scores_gemma":[0.0005683489,0.0002120418,0.000332609,0.001918721,0.0006396862,0.002269287,0.0006143429,0.001543386,0.002963061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005904385,"about_ca_system_score_gemma":0.0009461549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009360077,"about_ca_topic_score_gemma":0.001657057,"domain_scores_codex":[0.999838,0.00002665673,0.00002289794,0.00003218677,0.00006406332,0.00001621216],"domain_scores_gemma":[0.9997063,0.0001081424,0.00003927373,0.000008949551,0.0000871005,0.00005014886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001025254,0.00008387405,0.0002522414,0.01469836,0.00008484103,0.0004700008,0.0001535083,0.0001576449,0.004791926,0.004077223,0.0520274,0.9231005],"study_design_scores_gemma":[0.00001400916,0.0001296011,0.0008444448,0.001863267,0.00006529397,0.001942124,0.0001379822,0.00004640827,0.001037803,0.002883207,0.9910135,0.00002238139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001052229,0.9978661,0.00009620216,0.0005530706,0.0007698613,0.000002646242,0.000006717521,0.000004569315,0.0005957078],"genre_scores_gemma":[0.0005398487,0.9975125,0.0001416399,0.000258288,0.0007184288,0.000003203191,0.00001079751,0.000001217405,0.0008141202],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004201456,"threshold_uncertainty_score":0.01405525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02779188985242027,"score_gpt":0.3684969059885045,"score_spread":0.3407050161360842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}