{"id":"W2017012269","doi":"10.1016/j.molmed.2005.03.008","title":"Genetic therapies for cardiovascular diseases","year":2005,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Clinical trial; Disease; Intensive care medicine; Myocardial ischemia; Bioinformatics; Ischemia; Pathology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001951304,0.000552843,0.001501044,0.0003697416,0.00003256516,0.00001055405,0.0003874135,0.0003469108,0.00004964499],"category_scores_gemma":[0.00008368331,0.0004524184,0.001322786,0.0003165279,0.0001076006,0.000001292361,0.00008352521,0.0001692938,0.000003630163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003619027,"about_ca_system_score_gemma":0.00006377349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009470185,"about_ca_topic_score_gemma":0.00001039405,"domain_scores_codex":[0.9979438,0.0001000842,0.0005587085,0.0007140117,0.0002540462,0.0004293192],"domain_scores_gemma":[0.9987619,0.00002653897,0.00009866705,0.0009400654,0.00004086713,0.0001319556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006241838,0.00002920389,0.000002633412,0.001379637,0.0007896257,0.00002741067,0.00001909833,0.000290476,0.0001407578,0.00001641707,0.0009458979,0.9963526],"study_design_scores_gemma":[0.0007371365,0.0002083049,0.00003321444,0.001304292,0.001673274,0.00004479432,0.00001043157,0.0000156115,0.0000330975,0.00001661043,0.9954686,0.0004546569],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001278053,0.9765139,0.02244246,0.00004184033,0.0002595583,0.0004491182,0.00005397196,0.00002203574,0.0002043079],"genre_scores_gemma":[0.0001637303,0.9941567,0.002581763,0.00007606732,0.001243926,0.0004047371,0.0007822285,0.0001368877,0.0004539145],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9958979,"threshold_uncertainty_score":0.9997928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02111102578355762,"score_gpt":0.3645370505922271,"score_spread":0.3434260248086695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}