{"id":"W2017196173","doi":"10.1016/j.ydbio.2012.07.027","title":"Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1","year":2012,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Morphogenesis; Patched; Proto-oncogene tyrosine-protein kinase Src; Mammary gland; Cell biology; Internal medicine; Endocrinology; Hedgehog; Signal transduction; Cancer; Genetics; Gene; Breast cancer; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003071098,0.0001764423,0.0002498241,0.00005424991,0.0001128128,0.000002898292,0.0005794396,0.0001585754,0.000003409348],"category_scores_gemma":[0.0002286476,0.0000905443,0.00008793319,0.0002773478,0.0001350977,0.00000484985,0.0007703677,0.00007073682,0.000003215964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002143886,"about_ca_system_score_gemma":0.0001023022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009529156,"about_ca_topic_score_gemma":0.00003478402,"domain_scores_codex":[0.9987104,0.0002762733,0.0003885879,0.0002298418,0.0001253634,0.0002695649],"domain_scores_gemma":[0.9991283,0.00007433902,0.0001975154,0.0004195942,0.0001278282,0.00005243221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001356512,0.00005782229,0.01788597,0.00001761222,0.00008054111,8.115741e-7,0.0006820161,0.000009071307,0.9783443,0.00001320143,0.0007005766,0.002072374],"study_design_scores_gemma":[0.0001911031,0.0001137218,0.1276584,0.00003371777,0.00001296766,0.00002426356,0.0001869434,7.997227e-7,0.8678184,0.000009466917,0.003846622,0.0001036038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976763,0.0004245641,0.0005017524,0.0005557869,0.0002280078,0.0004288951,0.00009249651,0.000006924827,0.00008531694],"genre_scores_gemma":[0.9978887,0.00008035322,0.001486337,0.0002865666,0.00007427449,0.00005882761,0.00004894599,0.00001314408,0.0000628413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.110526,"threshold_uncertainty_score":0.369229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01408899272186465,"score_gpt":0.2388358897111847,"score_spread":0.2247468969893201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}