{"id":"W2017207034","doi":"10.1517/17530059.1.2.169","title":"The mitochondrial genome: a biosensor for early cancer detection?","year":2007,"lang":"en","type":"article","venue":"Expert Opinion on Medical Diagnostics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pyrogenesis (Canada)","funders":"","keywords":"Mitochondrial DNA; Mitochondrion; Cancer; Biology; Genome; Human mitochondrial genetics; Mutation; Cancer research; Cancer cell; Heteroplasmy; DNAJA3; Genetics; Gene; mitochondrial fusion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001360368,0.001006198,0.001139724,0.0008771794,0.0003479254,0.001460525,0.001337793,0.0056039,0.003699624],"category_scores_gemma":[0.002236357,0.0004501441,0.0004813034,0.0006271328,0.001173385,0.00279523,0.0006847673,0.002171102,0.003276407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007815631,"about_ca_system_score_gemma":0.0003564857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002830658,"about_ca_topic_score_gemma":0.0004379462,"domain_scores_codex":[0.9991609,0.000283218,0.00002850863,0.0001567163,0.0002900864,0.0000806941],"domain_scores_gemma":[0.9993469,0.0002875267,0.000071754,0.00005372307,0.0001744037,0.00006572139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0006167722,0.0001657421,0.003138119,0.003036736,0.0001581148,0.001081672,0.0002834884,0.0004675966,0.6013553,0.02158111,0.03583378,0.3322815],"study_design_scores_gemma":[0.0001109996,0.001319617,0.003497676,0.001009399,0.0002324491,0.01125352,0.0007637466,0.007028664,0.5460545,0.03234085,0.3962039,0.0001847655],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02993157,0.6939054,0.1648345,0.0822677,0.008463337,0.0001227829,0.0004510079,0.001425468,0.01859829],"genre_scores_gemma":[0.3632364,0.3976115,0.1777489,0.02993912,0.004233886,0.0003634184,0.0005953652,0.0001758736,0.02609545],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0056039,"threshold_uncertainty_score":0.01237649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.017228815162089,"score_gpt":0.3227797928104515,"score_spread":0.3055509776483625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}