{"id":"W2017207945","doi":"10.1371/journal.pcbi.0040036","title":"Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens","year":2008,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Microbial Fuel Cells and Bioremediation","field":"Environmental Science","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Office of Science; U.S. Department of Energy","keywords":"Geobacter sulfurreducens; In silico; Oxidoreductase; Metabolic pathway; Flux balance analysis; Computational biology; Geobacter; Metabolic network; Biology; Biochemistry; Citric acid cycle; Mutant; Ferredoxin; Enzyme; Chemistry; Gene; Genetics; Bacteria; Biofilm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008645783,0.00006948691,0.000178308,0.00008638509,0.00004094264,0.000002617839,0.00009618654,0.00003849552,0.0003080176],"category_scores_gemma":[0.00001171344,0.00005097419,0.00005342256,0.0003460051,0.0003157237,0.00004575232,0.00004536721,0.00003896391,0.000003434563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002007176,"about_ca_system_score_gemma":0.00001361879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002492373,"about_ca_topic_score_gemma":0.00003607417,"domain_scores_codex":[0.9992425,0.00009377316,0.0002580502,0.0001552179,0.0001381089,0.0001123524],"domain_scores_gemma":[0.9996623,0.0001354429,0.0001116531,0.00005176693,0.0000161624,0.00002271499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004641185,0.0006002188,0.7634367,0.00000833432,0.0001692456,0.000002454732,0.004488053,0.1269531,0.101951,0.001965292,0.0001848465,0.0001944094],"study_design_scores_gemma":[0.0002741933,0.00003547769,0.9759634,0.000001743191,0.00004980706,0.000005330342,0.00006719664,0.01919861,0.003394286,0.000875554,0.00007196197,0.00006244388],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992116,0.00009616575,0.000227557,0.000129565,0.00003293701,0.00009908011,0.00005862889,0.00000296549,0.0001415159],"genre_scores_gemma":[0.9974922,0.00001101055,0.002103974,0.000104335,0.00001616962,0.00000297613,0.000263284,0.000002296118,0.000003777441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2125267,"threshold_uncertainty_score":0.3372577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524981260435589,"score_gpt":0.2321640451583837,"score_spread":0.2169142325540279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}