{"id":"W2017282071","doi":"10.1038/sj.embor.7400537","title":"The RING‐finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila","year":2005,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Cancer Institute; Japan Society for the Promotion of Science","keywords":"Ubiquitin ligase; Innate immune system; Cell biology; Scaffold protein; Biology; Ubiquitin; Transcription factor; Activator (genetics); Kinase; Ring finger; Immunity; Immune system; Drosophila melanogaster; Signal transduction; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002202974,0.000248844,0.000463102,0.0001669424,0.0003039963,0.00002397823,0.0003092372,0.0002521977,0.0002933926],"category_scores_gemma":[0.0004653418,0.0001951239,0.0001422999,0.0002236203,0.0001349836,0.0001060148,0.0001498147,0.000425836,0.0001638682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001133626,"about_ca_system_score_gemma":0.0001510135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002777081,"about_ca_topic_score_gemma":0.000140436,"domain_scores_codex":[0.9974761,0.000491335,0.0009738657,0.0003608654,0.0001021435,0.0005956604],"domain_scores_gemma":[0.9984928,0.0001959031,0.0004466632,0.0006981606,0.0001311476,0.00003531669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003475365,0.0001609532,0.0002992174,0.0000119564,0.00009948857,0.00009112214,0.000541668,0.0002837603,0.9946757,0.00113011,0.0003260922,0.002032372],"study_design_scores_gemma":[0.0008678099,0.0001764344,0.002102248,0.000126158,0.00002138218,0.0002143846,0.0001183026,0.00007428657,0.9784036,0.001066253,0.01658137,0.0002478265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930552,0.00294703,0.0003501042,0.0009323909,0.0005302913,0.001107297,0.000006896606,0.00006555415,0.001005299],"genre_scores_gemma":[0.9968472,0.00001532892,0.0002312043,0.000225138,0.00004142905,0.0001558073,0.0000146647,0.00003212913,0.002437175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01627217,"threshold_uncertainty_score":0.795692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009240986387581104,"score_gpt":0.2262080511518676,"score_spread":0.2169670647642865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}