{"id":"W2017287154","doi":"10.1186/1471-2466-14-4","title":"A blinded evaluation of the efficacy and safety of glycopyrronium, a once-daily long-acting muscarinic antagonist, versus tiotropium, in patients with COPD: the GLOW5 study","year":2014,"lang":"en","type":"article","venue":"BMC Pulmonary Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Western Hospital; University Health Network","funders":"Grifols; Apellis Pharmaceuticals; Novartis Pharma; Ablynx; CSL Behring; University Health Network; GlaxoSmithKline; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; AstraZeneca; Pfizer","keywords":"Medicine; COPD; Muscarinic antagonist; Tiotropium bromide; Lama; Glycopyrrolate; Anesthesia; Internal medicine; Muscarinic acetylcholine receptor; Lung function; Lung; Atropine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001971885,0.0003133861,0.0007019714,0.000204165,0.0001704927,0.000007761587,0.0003627153,0.00009415871,0.0001397279],"category_scores_gemma":[0.001463071,0.0001708522,0.00008276568,0.0008967099,0.0009506002,0.0001151028,0.0002413318,0.0004843807,0.000002450361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004463259,"about_ca_system_score_gemma":0.0006982741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005903364,"about_ca_topic_score_gemma":0.0004087452,"domain_scores_codex":[0.9949102,0.0009790648,0.0007992252,0.0005589522,0.002338392,0.0004141695],"domain_scores_gemma":[0.9966949,0.0009806262,0.0004552798,0.001058101,0.0006384807,0.0001726158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02288448,0.001742137,0.9485755,0.0004444408,0.000164722,0.00001146891,0.001013011,0.0001937577,0.0001938025,0.00003330913,0.0000283745,0.02471502],"study_design_scores_gemma":[0.04019382,0.002360889,0.947598,0.0006960566,0.0007342678,0.00001072072,0.002269995,0.005854504,0.00003890213,0.00002113827,0.00007859791,0.0001430626],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920616,0.0006772623,0.00002961924,0.0005269028,0.0003134931,0.004217244,0.00001548459,0.00001881461,0.002139598],"genre_scores_gemma":[0.999463,0.00002426734,0.00004328725,0.00003532647,0.0002153985,0.0000785026,0.00004453922,0.00004024671,0.00005542278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02457195,"threshold_uncertainty_score":0.6967149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04403495813878711,"score_gpt":0.3347658076452596,"score_spread":0.2907308495064725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}