{"id":"W2017287154","doi":"10.1186/1471-2466-14-4","title":"A blinded evaluation of the efficacy and safety of glycopyrronium, a once-daily long-acting muscarinic antagonist, versus tiotropium, in patients with COPD: the GLOW5 study","year":2014,"lang":"en","type":"article","venue":"BMC Pulmonary Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Western Hospital; University Health Network","funders":"Grifols; Apellis Pharmaceuticals; Novartis Pharma; Ablynx; CSL Behring; University Health Network; GlaxoSmithKline; Canadian Institutes of Health Research; Teva Pharmaceutical Industries; AstraZeneca; Pfizer","keywords":"Medicine; COPD; Muscarinic antagonist; Tiotropium bromide; Lama; Glycopyrrolate; Anesthesia; Internal medicine; Muscarinic acetylcholine receptor; Lung function; Lung; Atropine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008973602,0.001619373,0.003464531,0.0004340804,0.0005055922,0.001045747,0.001025237,0.002765693,0.004306273],"category_scores_gemma":[0.00845167,0.0008023818,0.003001201,0.0003336358,0.001837278,0.001165301,0.0008446456,0.001822682,0.0007572699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009643873,"about_ca_system_score_gemma":0.001784383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005304349,"about_ca_topic_score_gemma":0.000697131,"domain_scores_codex":[0.9936146,0.004317433,0.0006108956,0.0007243829,0.0004366307,0.000296211],"domain_scores_gemma":[0.9926846,0.002207326,0.002914565,0.0009085174,0.0003838505,0.0009011671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9853576,0.002439459,0.0009484824,0.0002882256,0.001003517,0.00001551012,0.00004207071,0.0001551109,0.001826537,0.00006175296,0.0002101046,0.00765153],"study_design_scores_gemma":[0.8852373,0.1093534,0.002831414,0.00004632977,0.0009129271,0.00002985917,0.00001678637,0.0004540909,0.000593369,0.0001376064,0.000364031,0.00002289938],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990126,0.002880526,0.001263441,0.0003357192,0.0002968374,0.003306725,0.0007347539,0.00005796121,0.0009980662],"genre_scores_gemma":[0.9926998,0.0007965213,0.001414494,0.0006290872,0.0003525684,0.002856837,0.0005217752,0.00001352028,0.0007154188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008973602,"threshold_uncertainty_score":0.04745752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04403495813878711,"score_gpt":0.3347658076452596,"score_spread":0.2907308495064725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}