{"id":"W2017315930","doi":"10.1016/j.jconrel.2009.11.012","title":"Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes","year":2009,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":310,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal","funders":"National Science Council; Canada Research Chairs","keywords":"Paclitaxel; Biocompatibility; Micelle; Polyester; Amphiphile; Nanoparticle; Drug delivery; Chemistry; Drug carrier; Nanotechnology; Copolymer; Materials science; Polymer; Organic chemistry; Aqueous solution; Surgery; Medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001345879,0.000382448,0.00251444,0.000233491,0.0001328234,0.0001258784,0.0005227902,0.0001462775,0.00003937309],"category_scores_gemma":[0.0004854538,0.0002048196,0.001075175,0.0001441592,0.0002001971,0.0001713829,0.00003889677,0.0002270773,0.000006925295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005882636,"about_ca_system_score_gemma":0.0007317593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001145022,"about_ca_topic_score_gemma":0.000004116604,"domain_scores_codex":[0.9966103,0.0005090271,0.001851713,0.0002300823,0.000446402,0.0003524958],"domain_scores_gemma":[0.9929613,0.003368278,0.002738002,0.0003390593,0.0004038475,0.0001894644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01146364,0.001036016,0.0000133084,0.00806306,0.0007369302,0.0001946412,0.0001346592,0.0004832944,0.07061301,0.00008532119,0.002025686,0.9051504],"study_design_scores_gemma":[0.06842277,0.005494712,0.00001907929,0.03530964,0.02517672,0.0008186743,0.000390194,0.002678145,0.04597159,0.0003208801,0.8137043,0.001693258],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.092807,0.9053019,0.00008152794,0.0002554012,0.0004067348,0.001063428,0.00007065723,0.00001047184,0.000002891727],"genre_scores_gemma":[0.06900313,0.929785,0.0005647909,0.0001693583,0.0003417415,0.00005283883,0.000002417357,0.00003703488,0.00004374594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9034572,"threshold_uncertainty_score":0.83523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506714265056624,"score_gpt":0.2871235429906379,"score_spread":0.2620564003400716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}