{"id":"W2017350327","doi":"10.1097/qai.0b013e3182a4b9ad","title":"Impact of Autologous Dendritic Cell–Based Immunotherapy (AGS-004) on B- and T-Cell Subset Changes and Immune Activation in HIV-Infected Patients Receiving Antiretroviral Therapy","year":2013,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"CD38; Dendritic cell; Immunotherapy; Immunology; CD8; Immune system; T cell; Medicine; Antigen; Cytotoxic T cell; CD40; Biology; Stem cell; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002415799,0.0001728156,0.0004003066,0.0001507763,0.0002037214,0.0002616821,0.00007894674,0.000171971,0.0006596008],"category_scores_gemma":[0.0004142757,0.00009356158,0.0001887822,0.0001122815,0.0001456517,0.0001167142,0.0001295278,0.0003322918,0.0001118189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001311082,"about_ca_system_score_gemma":0.0001307572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001786031,"about_ca_topic_score_gemma":0.0002510625,"domain_scores_codex":[0.9998459,0.00006836469,0.00001302413,0.00001944662,0.00002323003,0.00003003364],"domain_scores_gemma":[0.999844,0.00006312349,0.00002453913,0.00001073264,0.00001049638,0.00004713469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.03801497,0.005117827,0.3020259,0.0003063841,0.000461385,0.005749841,0.0009344103,0.001769196,0.4045272,0.0002915725,0.0007018803,0.2400994],"study_design_scores_gemma":[0.002938239,0.1165339,0.7643833,0.00007411538,0.0007919261,0.01415047,0.0005820216,0.00386864,0.0882137,0.0004034985,0.008016907,0.00004336627],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991965,0.0003006468,0.00003500879,0.00001786267,0.000004781199,0.000009960399,0.00001019849,0.000003807454,0.0004211496],"genre_scores_gemma":[0.9995294,0.0001140385,0.0001216809,0.00003589551,0.00001215293,0.000008066711,0.0000370333,0.000001277551,0.0001404572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006596008,"threshold_uncertainty_score":0.002206624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01154018300700085,"score_gpt":0.2517944868815895,"score_spread":0.2402543038745887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}