{"id":"W2017537456","doi":"10.1016/j.ymgme.2011.06.025","title":"Arginase I deficiency: Severe infantile presentation with hyperammonemia: More common than reported?","year":2011,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; U.S. Department of Health and Human Services; Rare Diseases Clinical Research Network; National Institutes of Health; Hospital for Sick Children","keywords":"Hyperammonemia; Failure to thrive; Medicine; Encephalopathy; Internal medicine; Urea cycle; Pediatrics; Lethargy; Arginase; Endocrinology; Arginine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001643338,0.000325335,0.0002935251,0.00008612752,0.0001262191,0.00004862241,0.0002328951,0.0001903352,0.00002642188],"category_scores_gemma":[0.00002623997,0.0002839201,0.00008955217,0.0001776901,0.0002121877,0.000007672615,0.0001615259,0.0001252084,0.000004465822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001632611,"about_ca_system_score_gemma":0.00008924741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534458,"about_ca_topic_score_gemma":0.00009577549,"domain_scores_codex":[0.9982718,0.00007927204,0.0003210463,0.0006263363,0.0002913568,0.0004101417],"domain_scores_gemma":[0.9987778,0.000004251798,0.0001573717,0.0007160194,0.0001322656,0.0002122858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005982726,0.0006734792,0.08372936,0.0001310178,0.0004735193,0.0002612734,0.002528855,0.0006181934,0.860732,0.002825163,0.001279517,0.04614935],"study_design_scores_gemma":[0.003063864,0.0003947883,0.3322734,0.00002462221,0.0006194731,0.0004253305,0.0007711677,0.0001520607,0.5822067,0.001228324,0.07762763,0.001212697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760275,0.01663354,0.002418645,0.0000553889,0.0001562889,0.00038583,0.00002653351,0.00002157437,0.004274679],"genre_scores_gemma":[0.9902306,0.001844648,0.006877291,0.0004143236,0.00007219252,0.00005107631,0.0001479512,0.00005816094,0.0003037936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2785254,"threshold_uncertainty_score":0.9999613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01015313244751148,"score_gpt":0.2321986066235934,"score_spread":0.2220454741760819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}