{"id":"W2017587511","doi":"10.1371/journal.pgen.1000414","title":"A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species","year":2009,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"National Institute of General Medical Sciences; National Institute on Aging; National Institutes of Health","keywords":"Biology; Longevity; Caenorhabditis elegans; Homologous chromosome; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161687,0.0001844409,0.0002086744,0.00004664549,0.0001571878,0.00004831559,0.0001545455,0.0001305033,0.00001241826],"category_scores_gemma":[0.00003469051,0.0001983145,0.00003567884,0.00009693993,0.0001102026,0.000008863183,0.00007517337,0.0001042049,0.000001150799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001037614,"about_ca_system_score_gemma":0.00004302561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009208354,"about_ca_topic_score_gemma":0.0001570205,"domain_scores_codex":[0.9989334,0.00005556856,0.0003247179,0.0003045762,0.0001535538,0.0002281607],"domain_scores_gemma":[0.9992775,0.000006673885,0.0001971823,0.0002634567,0.0001869347,0.00006819625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005513254,0.00006453707,0.04440013,0.0001363391,0.00004414306,6.30262e-7,0.0004091073,0.0002176854,0.9540429,0.00007378434,0.000333185,0.000272012],"study_design_scores_gemma":[0.0003182398,0.0005928319,0.01844347,0.00008750771,0.00007870913,0.000002585559,0.00009528948,0.0003046878,0.9773045,0.001364576,0.001150044,0.0002575212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977247,0.0006087136,0.0007606364,0.0002042389,0.00003078955,0.0003099477,0.00001014233,0.00001974096,0.0003310681],"genre_scores_gemma":[0.997499,0.0001130171,0.001259407,0.0002361264,0.0004627907,0.000008801933,0.0001238126,0.00002316562,0.0002739187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02595665,"threshold_uncertainty_score":0.8087031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03438722982273348,"score_gpt":0.2616291216258473,"score_spread":0.2272418918031138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}