{"id":"W2017592356","doi":"10.1097/00002030-200403050-00001","title":"Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy","year":2004,"lang":"en","type":"article","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Genotype; V3 loop; Viral load; Virology; Internal medicine; Cohort; Biology; Immunology; Medicine; Human immunodeficiency virus (HIV); Genetics; Gene; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008516508,0.000193076,0.0003531804,0.0002462282,0.0003854483,0.0005722124,0.0002212433,0.0004226054,0.001055478],"category_scores_gemma":[0.005369687,0.000101979,0.00024449,0.0004235267,0.0003047992,0.0002601386,0.0001929724,0.0006502985,0.0001939704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005392272,"about_ca_system_score_gemma":0.0003369125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005632492,"about_ca_topic_score_gemma":0.007443224,"domain_scores_codex":[0.9993352,0.0001896188,0.00004670871,0.0001170442,0.0001711343,0.0001402508],"domain_scores_gemma":[0.9966148,0.001196083,0.001237165,0.0001126696,0.0003522351,0.0004871311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002057429,0.0001207532,0.9875162,0.00001564008,0.00006232083,0.0005621754,0.0001217191,0.0001869576,0.001262186,0.00001333877,0.0001224218,0.007958977],"study_design_scores_gemma":[0.000009259775,0.000667226,0.9983016,0.000005397064,0.00002228804,0.000485246,0.00006637816,0.0001538473,0.0001811411,0.000014071,0.00008985359,0.000003582826],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993181,0.000220348,0.00002508465,0.0000215003,0.000003375024,0.000005340184,0.00006731907,0.000001804757,0.0003371122],"genre_scores_gemma":[0.9997537,0.00003193125,0.00001304242,0.00001307946,0.000003923839,0.000002282726,0.0001006449,7.554289e-7,0.0000807402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005632492,"threshold_uncertainty_score":0.01119941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04627176138158794,"score_gpt":0.3626794513613791,"score_spread":0.3164076899797911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}