{"id":"W2017608263","doi":"10.1074/jbc.m411023200","title":"General Enzymatic Screens Identify Three New Nucleotidases in Escherichia coli","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Core Research for Evolutional Science and Technology; National Institute of General Medical Sciences; Inamori Foundation; Genome Canada","keywords":"Biochemistry; Enzyme; Nucleotide; Escherichia coli; Phosphatase; Nucleoside; Deoxyribonucleoside; Pyrophosphatases; Adenylylation; Divalent; Ribonucleoside; Biology; Substrate (aquarium); Nucleotidase; Chemistry; RNA; Biosynthesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022769,0.0006682334,0.000492104,0.0004560098,0.0001448646,0.0005848077,0.0002905326,0.0004812934,0.0008175662],"category_scores_gemma":[0.0004375285,0.0002442226,0.0004670784,0.0005000948,0.0001753042,0.0001668331,0.0003676617,0.000555932,0.000671763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004011998,"about_ca_system_score_gemma":0.0002534525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001142041,"about_ca_topic_score_gemma":0.001645511,"domain_scores_codex":[0.9995949,0.00006026174,0.0000572842,0.00006938201,0.000151805,0.0000663756],"domain_scores_gemma":[0.9997866,0.00007034114,0.00003888335,0.00002871657,0.00003757668,0.00003797089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000501323,0.00003332237,0.0005769518,0.00004513558,0.000007985508,0.00009444781,0.000009534843,0.00007725503,0.9973643,0.00005748547,0.00004272055,0.001640735],"study_design_scores_gemma":[0.00001473893,0.0002781451,0.01042441,0.00001002638,0.00003527777,0.001190652,0.0000605909,0.00102987,0.9825895,0.00005525199,0.004300958,0.00001070389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766143,0.002369134,0.01302356,0.0003243951,0.00004198106,0.0002021676,0.003567208,0.0003743295,0.003482835],"genre_scores_gemma":[0.9518282,0.002497237,0.02866975,0.0003370501,0.00001819099,0.000175443,0.01047835,0.0001225168,0.005873308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142041,"threshold_uncertainty_score":0.002910912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506202894625325,"score_gpt":0.2722959066619161,"score_spread":0.2472338777156629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}