{"id":"W2017685660","doi":"10.1371/journal.pgen.1003312","title":"The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Biology; Population; Bacteriophage; Genetics; Phagemid; Plasmid; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001011945,0.0002609832,0.0003293787,0.0004678977,0.000408125,0.0008282997,0.0006680803,0.001047882,0.0007884004],"category_scores_gemma":[0.004044108,0.0003041464,0.0003732237,0.000316663,0.0008441564,0.00137479,0.0008275479,0.0004754263,0.0002072526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001256995,"about_ca_system_score_gemma":0.0005330774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001196303,"about_ca_topic_score_gemma":0.001074516,"domain_scores_codex":[0.9993605,0.0002064578,0.00002569249,0.0001998769,0.0001346822,0.0000726707],"domain_scores_gemma":[0.9986664,0.000597994,0.0003533249,0.0001147134,0.0001501774,0.0001174642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.0002738182,0.0002959023,0.1705918,0.0003612787,0.0003637277,0.001025406,0.001352836,0.3381525,0.2541228,0.1862321,0.001367838,0.04586004],"study_design_scores_gemma":[0.0000639365,0.0004535207,0.06411059,0.00003360946,0.0000913059,0.0009913162,0.000735547,0.8502754,0.01759625,0.05922339,0.006307303,0.0001178142],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9585981,0.0003812347,0.03732888,0.0002920074,0.00001206967,0.00002746523,0.00008169444,0.00005997614,0.003218408],"genre_scores_gemma":[0.9928855,0.0002149071,0.006043032,0.00004414777,0.000008491395,0.00004242088,0.00007931615,0.0000101831,0.0006718884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001256995,"threshold_uncertainty_score":0.009120226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004309908287911976,"score_gpt":0.2260790278254087,"score_spread":0.2217691195374967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}