{"id":"W2017685660","doi":"10.1371/journal.pgen.1003312","title":"The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Biology; Population; Bacteriophage; Genetics; Phagemid; Plasmid; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000405559,0.00008880924,0.00007554118,0.00001516994,0.00007554073,0.00001797975,0.00005327801,0.0000616983,0.000005030392],"category_scores_gemma":[0.00002739006,0.00006602861,0.00001188793,0.00003759915,0.00008136773,0.000002559531,0.00007163056,0.00004735034,6.817016e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005382963,"about_ca_system_score_gemma":0.00001105871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002823936,"about_ca_topic_score_gemma":0.00008418164,"domain_scores_codex":[0.9995556,0.00002300592,0.0001207987,0.000116718,0.00006866714,0.0001152056],"domain_scores_gemma":[0.9996338,0.00002076387,0.00004235738,0.0001893317,0.00006883244,0.00004493345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000464559,0.00005371214,0.09640608,0.00007551637,0.0001091912,5.587913e-7,0.00008404993,0.0002893599,0.8988634,0.0000561585,0.0001325125,0.003883041],"study_design_scores_gemma":[0.0006463637,0.000484601,0.7961234,0.00002664341,0.00006513931,0.00003103864,0.0002488449,0.03855374,0.1627274,0.0002377254,0.0005745571,0.0002805219],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968767,0.002103417,0.0006761995,0.00008274478,0.00002747913,0.0001625393,0.000015945,0.000005707675,0.00004933007],"genre_scores_gemma":[0.9975333,0.0009024752,0.001334717,0.00001454646,0.00003061497,0.0000120559,0.000113802,0.00001365826,0.00004487847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.736136,"threshold_uncertainty_score":0.2692569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004309908287911976,"score_gpt":0.2260790278254087,"score_spread":0.2217691195374967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}