{"id":"W2017687056","doi":"10.1021/acs.jafc.5b00882","title":"Synthesis, Biological Activity, and Conformational Study of N-Methylated Allatostatin Analogues Inhibiting Juvenile Hormone Biosynthesis","year":2015,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Ministry of Science and Technology of the People's Republic of China; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Juvenile hormone; Biosynthesis; Chemistry; Stereochemistry; Biochemistry; Biological activity; Hormone; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007882668,0.0002709399,0.0002061304,0.00009262688,0.00007648612,0.00009898505,0.0002125375,0.0001483461,0.000769283],"category_scores_gemma":[0.0001269665,0.00009444928,0.0002105359,0.0001155179,0.0001045468,0.0001643853,0.0001121503,0.0003145627,0.0001667895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001180576,"about_ca_system_score_gemma":0.0001134926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003453401,"about_ca_topic_score_gemma":0.0005099117,"domain_scores_codex":[0.9999619,0.000008166131,0.000004258972,0.00000756379,0.000008506509,0.000009638936],"domain_scores_gemma":[0.999944,0.000007269887,0.00001861698,0.000005183384,0.000009434753,0.00001552188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002039602,0.00004250844,0.0001436617,0.0001011588,0.00001335006,0.000116534,0.00002136041,0.0008158633,0.9952635,0.000107713,0.00003683637,0.003133604],"study_design_scores_gemma":[0.00009866567,0.002722976,0.002316454,0.00001188378,0.000056221,0.0003403078,0.00003565866,0.001334358,0.9884745,0.00006928834,0.004521808,0.00001785278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927998,0.002677342,0.002154431,0.00003739616,0.00002331464,0.00005605537,0.0002242722,0.00001908676,0.002008346],"genre_scores_gemma":[0.9936721,0.002439962,0.002317517,0.00004648328,0.00001008362,0.00002834299,0.0003181776,0.000007677282,0.001159529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000769283,"threshold_uncertainty_score":0.00257355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824472065866488,"score_gpt":0.2258928619577256,"score_spread":0.2076481412990607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}