{"id":"W2017720960","doi":"10.1093/carcin/bgh274","title":"Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines","year":2004,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Cancer Research Society; Calgary Laboratory Services","keywords":"Cell cycle; Hypoxia (environmental); Cell culture; Biology; Cell cycle checkpoint; HeLa; Protein kinase B; Cancer research; Kinase; Cell; Endocrinology; Internal medicine; Molecular biology; Phosphorylation; Cell biology; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039148,0.0002899186,0.0002856181,0.0005857632,0.0002506239,0.0002533256,0.0002032358,0.0001728741,0.003027982],"category_scores_gemma":[0.0001816139,0.0001272567,0.0001735729,0.0007663555,0.0001405125,0.0001389385,0.0001211405,0.0003263829,0.0006965804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000375227,"about_ca_system_score_gemma":0.0002969441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002413101,"about_ca_topic_score_gemma":0.00257607,"domain_scores_codex":[0.9997676,0.00004011753,0.00003331663,0.00005015232,0.00006261136,0.00004622469],"domain_scores_gemma":[0.9998585,0.00004281799,0.000022688,0.00002593355,0.00003450182,0.00001558916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000369675,0.0001187067,0.0009490228,0.00008329995,0.00001265157,0.00008061859,0.00006202512,0.0001299566,0.9947876,0.0001767029,0.000287177,0.002942562],"study_design_scores_gemma":[0.00003951046,0.0006226547,0.01697192,0.00001132992,0.00003009698,0.0005529475,0.00004484202,0.0009286567,0.9727572,0.00004958624,0.007984241,0.000006892077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722482,0.008349271,0.006843223,0.0001485891,0.00006469426,0.000254445,0.006213765,0.0002684319,0.005609481],"genre_scores_gemma":[0.953752,0.007253897,0.009663602,0.0001031818,0.00002836778,0.0007472988,0.02071979,0.00005792465,0.007673763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003027982,"threshold_uncertainty_score":0.01012957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083030159515962,"score_gpt":0.2442787448489081,"score_spread":0.2334484432537485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}