{"id":"W2017720960","doi":"10.1093/carcin/bgh274","title":"Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines","year":2004,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Cancer Research Society; Calgary Laboratory Services","keywords":"Cell cycle; Hypoxia (environmental); Cell culture; Biology; Cell cycle checkpoint; HeLa; Protein kinase B; Cancer research; Kinase; Cell; Endocrinology; Internal medicine; Molecular biology; Phosphorylation; Cell biology; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001097045,0.0003212521,0.000303797,0.00007730538,0.0001582539,0.00003674184,0.0002074588,0.000284189,0.0000287538],"category_scores_gemma":[0.00001205846,0.0003223686,0.0001235911,0.0001331097,0.00006859214,0.00001480317,0.0001768619,0.0001184181,0.000006136912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000620198,"about_ca_system_score_gemma":0.0001601662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001967379,"about_ca_topic_score_gemma":0.001103802,"domain_scores_codex":[0.9983171,0.00005936965,0.0003149725,0.0006812302,0.0001717676,0.0004555492],"domain_scores_gemma":[0.9990889,0.000009036736,0.000119482,0.000478796,0.00007762215,0.0002261615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005394331,0.0001889329,0.001831107,0.00009789203,0.000005164905,0.000007131894,0.0002001495,0.0003522744,0.9958871,0.000002357975,0.0005883641,0.0007855789],"study_design_scores_gemma":[0.002384238,0.0001058681,0.00982121,0.00004070018,0.00004127355,0.00000229341,0.000209062,0.000007444813,0.9819496,0.00003445379,0.004996937,0.0004069149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9688523,0.02887135,0.00002050357,0.00004732497,0.001016445,0.0002927134,0.00005575471,0.00002163223,0.0008219408],"genre_scores_gemma":[0.9940337,0.002798669,0.000208234,0.0002002564,0.002110178,0.0001046917,0.00006039498,0.00006522149,0.0004186825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02607268,"threshold_uncertainty_score":0.9999228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083030159515962,"score_gpt":0.2442787448489081,"score_spread":0.2334484432537485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}