{"id":"W2017782459","doi":"10.1016/j.metabol.2010.07.015","title":"Genetics of pain, opioids, and opioid responsiveness","year":2010,"lang":"en","type":"review","venue":"Metabolism","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Opioid; Neuropathic pain; Medicine; Pharmacology; Candidate gene; Chronic pain; Bioinformatics; Neuroscience; Biology; Genetics; Internal medicine; Gene; Receptor; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007311927,0.0003714494,0.002192837,0.0002278851,0.0000435195,0.00001201126,0.0001260472,0.0004554957,0.00005923649],"category_scores_gemma":[0.0002770537,0.0002620183,0.0003212327,0.000183576,0.0000826859,0.0000183229,0.00008612004,0.0003726469,0.00001721476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001417782,"about_ca_system_score_gemma":0.0003094229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001395936,"about_ca_topic_score_gemma":0.000001691149,"domain_scores_codex":[0.9983686,0.0003065462,0.0004826217,0.0003610321,0.0002480213,0.0002331377],"domain_scores_gemma":[0.998623,0.0002137314,0.0002768748,0.0005920247,0.000120549,0.0001738571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001269356,0.00007262459,0.00001187726,0.007052392,0.0002172974,0.00004193091,0.00003310086,6.057575e-9,0.00003891893,0.0006309172,0.00008048576,0.9918078],"study_design_scores_gemma":[0.0005158294,0.00007645458,0.0002066407,0.003398929,0.002990527,0.0000731299,0.000006594452,0.000001856003,0.00007648157,0.0002678204,0.9921992,0.0001865713],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002133429,0.9980917,0.0001075376,0.00001598966,0.0004402918,0.0008393101,0.00007997091,0.00002271147,0.0001891302],"genre_scores_gemma":[0.00001085165,0.9930228,0.005440918,0.00009467176,0.0002707917,0.00007620964,0.00009812768,0.00006533875,0.0009203198],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9921187,"threshold_uncertainty_score":0.9999832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343149480041785,"score_gpt":0.333499889313484,"score_spread":0.2991849413093055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}