{"id":"W2017900496","doi":"10.1177/1740774506073463","title":"Independent design and conduct of clinical trials","year":2006,"lang":"en","type":"article","venue":"Clinical Trials","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Cornerstone; Independence (probability theory); Clinical trial; Randomized controlled trial; Alternative medicine; Medicine; Intervention (counseling); Intensive care medicine; Medical physics; Psychology; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","insufficient_payload"],"consensus_categories":["metaresearch","insufficient_payload"],"category_scores_codex":[0.7050918,0.0002652585,0.008818048,0.0002424339,0.0001020078,0.00008761567,0.0003612062,0.0007467327,0.0009580264],"category_scores_gemma":[0.4456395,0.0002637491,0.001154279,0.0001598501,0.0003694173,0.0002750101,0.00009722027,0.0004784262,0.0008626148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007075726,"about_ca_system_score_gemma":0.000394553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003902678,"about_ca_topic_score_gemma":0.00001967762,"domain_scores_codex":[0.8683526,0.05328716,0.07587481,0.001587414,0.0002621895,0.0006358085],"domain_scores_gemma":[0.6862709,0.278192,0.0332878,0.001364267,0.0002404493,0.0006446389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001102122,0.00164203,0.3694689,0.0004543778,0.001030255,0.000006775692,0.0001848174,0.0002909951,0.00002843056,0.2871261,0.3262103,0.01245491],"study_design_scores_gemma":[0.02821955,0.001588707,0.3150925,0.0003085641,0.0003014936,0.00001105173,0.000405493,0.005645293,0.0001177894,0.4139661,0.2330491,0.001294414],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8128814,0.01432895,0.09438601,0.0459777,0.0130615,0.00892874,0.001166917,0.0001831203,0.009085659],"genre_scores_gemma":[0.9537289,0.001828411,0.02729309,0.007939251,0.007291466,0.0001719168,0.00005397377,0.0000778483,0.001615179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2594524,"threshold_uncertainty_score":0.9999815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9586008366553108,"score_gpt":0.6906928632390332,"score_spread":0.2679079734162776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}