{"id":"W2017932566","doi":"10.3109/09546634.2013.865009","title":"The 5-point Investigator’s Global Assessment (IGA) Scale: A modified tool for evaluating plaque psoriasis severity in clinical trials","year":2013,"lang":"en","type":"review","venue":"Journal of Dermatological Treatment","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":261,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"","keywords":"Secukinumab; Medicine; Psoriasis Area and Severity Index; Psoriasis; Clinical endpoint; Clinical trial; Surrogate endpoint; Internal medicine; Dermatology; Immunology; Psoriatic arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.009112358,0.0009797831,0.006947607,0.0001541644,0.0004126049,0.0001392147,0.0007340197,0.001654529,0.0000839194],"category_scores_gemma":[0.004438059,0.0004578274,0.003949901,0.0002975985,0.000345815,0.0001495983,0.0001446857,0.0007809598,0.00007811054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001326227,"about_ca_system_score_gemma":0.002024145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001787038,"about_ca_topic_score_gemma":0.00001924278,"domain_scores_codex":[0.9801594,0.01186666,0.006292042,0.0006566793,0.0002222334,0.0008030013],"domain_scores_gemma":[0.9818218,0.01243703,0.004653011,0.0005950455,0.0002804864,0.0002125771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000441501,0.001205515,0.001617778,0.0004408419,0.004191262,0.0001006664,0.00002764474,0.000003480847,0.000003556514,0.0003775478,0.0032601,0.9883301],"study_design_scores_gemma":[0.02317476,0.005023003,0.003035892,0.005254388,0.01679244,0.00467394,0.0001820301,0.00004876215,0.00007918467,0.003990951,0.9364541,0.001290592],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01192216,0.9792568,0.0001810795,0.0007496738,0.002928921,0.004359562,0.0004380293,0.00003513327,0.0001286416],"genre_scores_gemma":[0.0013637,0.9933552,0.003099809,0.0001002084,0.0002751407,0.001443365,0.0001798751,0.00003620359,0.0001465302],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9870395,"threshold_uncertainty_score":0.9997873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3175616168721397,"score_gpt":0.490082295512084,"score_spread":0.1725206786399443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}