{"id":"W2017967132","doi":"10.1016/j.intimp.2014.09.002","title":"Adenosine 5′-monophosphate-induced hypothermia inhibits the activation of ERK1/2, JNK, p38 and NF-κB in endotoxemic rats","year":2014,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Thermal Regulation in Medicine","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"p38 mitogen-activated protein kinases; Western blot; Kinase; Signal transduction; Inflammation; TLR4; MAPK/ERK pathway; NF-κB; Internal medicine; Endocrinology; Lipopolysaccharide; Chemistry; Pharmacology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001902699,0.0006887692,0.0004556871,0.0002801693,0.0001985854,0.0001846206,0.0002950437,0.0002493478,0.00181792],"category_scores_gemma":[0.0001390101,0.0002650091,0.0005118328,0.00015193,0.0003660643,0.000324871,0.000177714,0.001106715,0.0002391691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173094,"about_ca_system_score_gemma":0.0003498186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006045336,"about_ca_topic_score_gemma":0.001108948,"domain_scores_codex":[0.9998764,0.00001416493,0.00001203971,0.00002095894,0.00002023298,0.00005617378],"domain_scores_gemma":[0.999866,0.000007848287,0.00005521541,0.00001494653,0.000009377434,0.00004657752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006505563,0.0004392822,0.0003657764,0.0001370394,0.00003306652,0.0001059016,0.00005676677,0.0001682506,0.9877001,0.0002448487,0.0001677088,0.004075734],"study_design_scores_gemma":[0.0003773101,0.004192856,0.01359541,0.0000288414,0.0001184477,0.000211367,0.0001198502,0.001466698,0.9782934,0.0002217032,0.001349713,0.00002440786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99581,0.001214362,0.001694958,0.0001669905,0.00008717582,0.00003057904,0.0001856488,0.00008066314,0.0007297394],"genre_scores_gemma":[0.9950861,0.00112646,0.001050446,0.00007087549,0.00004106405,0.00009147459,0.000258854,0.00001592719,0.002258791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00181792,"threshold_uncertainty_score":0.006081522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402605597542271,"score_gpt":0.3022383875334443,"score_spread":0.2882123315580216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}