{"id":"W2017994198","doi":"10.1073/pnas.161151798","title":"DNA damage-inducible gene <i>p33ING2</i> negatively regulates cell proliferation through acetylation of p53","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"","keywords":"Transactivation; Acetylation; DNA damage; Cell growth; Cell cycle; Cell biology; Biology; Apoptosis; Cell cycle checkpoint; DNA; Molecular biology; Regulator; DNA repair; Gene; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009290928,0.0001222746,0.0002355455,0.0001855199,0.0001512623,0.0000142302,0.0003331106,0.000141324,0.00001990327],"category_scores_gemma":[0.0004655528,0.00009002757,0.000101622,0.001359776,0.0005910277,0.0005776994,0.00008373452,0.000197057,0.000001505729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007536627,"about_ca_system_score_gemma":0.0001239426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000117026,"about_ca_topic_score_gemma":1.477634e-7,"domain_scores_codex":[0.9977033,0.000009501213,0.0004792997,0.0002944227,0.001348251,0.0001652899],"domain_scores_gemma":[0.9984617,0.00005881635,0.0007338023,0.00001787369,0.0006903485,0.00003751194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006681358,0.00009001126,0.003107057,0.00009048925,0.00001937045,1.777753e-8,0.0006386142,0.0004004395,0.9903026,0.004547934,0.0005631449,0.0001734933],"study_design_scores_gemma":[0.0006061363,0.0001478183,0.02069853,0.0001808714,0.00004453089,0.00002087739,0.0001866604,0.001785029,0.9640869,0.01197669,0.0001865616,0.00007939091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817809,0.0002232347,0.00002088559,0.003224676,0.00002687726,0.0004565331,0.000008266785,0.0000182949,0.01424026],"genre_scores_gemma":[0.9940502,0.00009115899,0.005128701,0.0002765189,0.00009716527,0.00001195233,0.00000109578,0.000008950007,0.0003342262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02621571,"threshold_uncertainty_score":0.3671218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04664781843420088,"score_gpt":0.303032383562269,"score_spread":0.2563845651280681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}