{"id":"W2018021370","doi":"10.1002/phar.1500","title":"Serotonin Toxicity Association with Concomitant Antidepressants and Rasagiline Treatment: Retrospective Study (<scp>STACCATO</scp>)","year":2014,"lang":"en","type":"article","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"Teva Pharmaceutical Industries","keywords":"Medicine; Serotonin syndrome; Rivastigmine; Retrospective cohort study; Antidepressant; Rasagiline; Internal medicine; Selegiline; Serotonin reuptake inhibitor; Dementia; Serotonin; Parkinson's disease; Disease; Serotonergic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00132622,0.0003621371,0.0007325009,0.0001582133,0.0004555048,0.00003945082,0.000139591,0.00006875834,0.0001007569],"category_scores_gemma":[0.00001548539,0.0002027548,0.0001062353,0.0001388344,0.000129589,0.0001916328,0.00002003914,0.0003672879,0.000001844694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002302578,"about_ca_system_score_gemma":0.00007097309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002987153,"about_ca_topic_score_gemma":0.00001369859,"domain_scores_codex":[0.9976898,0.00088518,0.0004339313,0.0002836827,0.0003665992,0.0003408289],"domain_scores_gemma":[0.9982377,0.0004228887,0.0007001948,0.0001524858,0.0002263577,0.0002603157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003568375,0.0033898,0.658837,0.0000129884,0.004409313,0.0001229215,0.005715802,0.00000838752,0.3187988,0.00002373734,0.001105302,0.004007611],"study_design_scores_gemma":[0.08822233,0.01356263,0.4260185,0.00005264704,0.00262382,0.0003725342,0.001200152,0.0003195755,0.4557843,0.0005482394,0.01106924,0.0002260214],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933976,0.004301079,0.00004084406,0.0006309432,0.0001918644,0.001228887,0.00001603677,0.00003244686,0.0001603044],"genre_scores_gemma":[0.9864494,0.01097801,0.00004751561,0.00167297,0.0003559134,0.00003902817,0.000002634192,0.00004379986,0.0004107578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2328185,"threshold_uncertainty_score":0.82681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651122181152179,"score_gpt":0.3194258784910625,"score_spread":0.3029146566795407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}