{"id":"W2018118610","doi":"10.1074/jbc.275.6.4467","title":"PILRα, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILRβ","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Immunoreceptor tyrosine-based activation motif; SH2 domain; Tyrosine; Biology; Transmembrane domain; Biochemistry; Tyrosine phosphorylation; Protein tyrosine phosphatase; Transmembrane protein; Phosphorylation; Molecular biology; Cell biology; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008643221,0.0004134385,0.000180382,0.0001671565,0.0001113644,0.0002391434,0.0002054266,0.000198582,0.0008766247],"category_scores_gemma":[0.00008304494,0.0001129664,0.0002322852,0.000140939,0.000179878,0.0001106625,0.0002194023,0.00034937,0.0008253119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002513363,"about_ca_system_score_gemma":0.0001076617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002178857,"about_ca_topic_score_gemma":0.0003467779,"domain_scores_codex":[0.9999028,0.00001326284,0.000004690668,0.00002410246,0.00002826311,0.00002688321],"domain_scores_gemma":[0.9999453,0.000005861834,0.00001952285,0.000006331659,0.000004655885,0.00001827301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003820428,0.000004420957,0.0001973181,0.00001286056,0.000001640111,0.00009629906,0.000004590265,0.00002383989,0.9989712,0.00004228377,0.00001831999,0.0005890103],"study_design_scores_gemma":[0.00002435971,0.0002307141,0.01811433,0.000007519726,0.00001910508,0.002350635,0.00003558576,0.001872427,0.9724214,0.00007331112,0.004844239,0.000006416505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922935,0.001194843,0.004607442,0.00007559717,0.00001678047,0.00002831058,0.000315088,0.0001198962,0.001348506],"genre_scores_gemma":[0.9918087,0.0007670533,0.003189909,0.00005545642,0.00001510992,0.00002328828,0.001445958,0.00002258653,0.002671808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008766247,"threshold_uncertainty_score":0.002932608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01642965469211634,"score_gpt":0.2233744495489346,"score_spread":0.2069447948568182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}