{"id":"W2018134501","doi":"10.1016/j.fgb.2009.07.004","title":"Metabolic control of antifungal drug resistance","year":2009,"lang":"en","type":"article","venue":"Fungal Genetics and Biology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Phenotype; Drug resistance; Saccharomyces cerevisiae; Candida albicans; Ergosterol; Calcineurin; Antifungal drug; Genetics; Cell biology; Computational biology; Microbiology; Gene; Biochemistry; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001965798,0.0003161161,0.0002659933,0.0003223554,0.0002683203,0.00117085,0.0002792932,0.0004693459,0.001159173],"category_scores_gemma":[0.0002546403,0.0001634723,0.0002406186,0.0002464872,0.0003008905,0.0005476653,0.0004457165,0.0004982423,0.0004075271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007613726,"about_ca_system_score_gemma":0.0001547204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005650605,"about_ca_topic_score_gemma":0.0006062823,"domain_scores_codex":[0.9998075,0.00004227633,0.00001320215,0.00004189352,0.00005791288,0.00003715343],"domain_scores_gemma":[0.9998732,0.00001902429,0.0000415352,0.00001695803,0.00002853837,0.00002087109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003518276,0.00002988618,0.0008935817,0.00006594909,0.00001372772,0.000163335,0.00003684308,0.0006618382,0.9759202,0.007851092,0.0003347412,0.01367702],"study_design_scores_gemma":[0.000025518,0.0001683296,0.01056718,0.00001846769,0.00001903534,0.0006890587,0.0001305645,0.007813392,0.9583496,0.00547264,0.01671809,0.00002807797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466226,0.01446673,0.01838046,0.002582344,0.0002127838,0.00003317204,0.000726199,0.0003080782,0.01666758],"genre_scores_gemma":[0.9948119,0.00152272,0.001576887,0.00007810608,0.00002165472,0.000006938123,0.0001895367,0.00002169505,0.001770551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00117085,"threshold_uncertainty_score":0.005524158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01429042913623744,"score_gpt":0.2798944831607888,"score_spread":0.2656040540245513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}