{"id":"W2018193192","doi":"10.3389/fmicb.2014.00381","title":"Production of a recombinant vaccine candidate against Burkholderia pseudomallei exploiting the bacterial N-glycosylation machinery","year":2014,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Glycoconjugate; Glycan; Glycosylation; Microbiology; Glycoprotein; Burkholderia pseudomallei; Biology; Immune system; Escherichia coli; Bacteria; Biochemistry; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006632453,0.0001696201,0.00044781,0.0002516415,0.000101026,0.000009200255,0.00009853422,0.0001612171,0.00004396483],"category_scores_gemma":[0.0002549614,0.0001207723,0.00009236312,0.0002861093,0.00008433693,0.00007188537,0.00004726382,0.0002363828,0.000005149845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009009139,"about_ca_system_score_gemma":0.00004846411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001699648,"about_ca_topic_score_gemma":0.00007996152,"domain_scores_codex":[0.9986536,0.0002155333,0.0004863141,0.0003220958,0.0000420229,0.0002804671],"domain_scores_gemma":[0.999256,0.00003718596,0.0002280961,0.0003547468,0.00008405765,0.00003994791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004440689,0.0001389683,0.04406158,0.0000665494,0.00006886166,0.000002069406,0.0002558861,0.00004581011,0.9272925,0.00004942951,0.01432556,0.01324876],"study_design_scores_gemma":[0.01849981,0.00243334,0.1843362,0.001155521,0.0005806466,0.001061409,0.00146129,0.003394976,0.4835579,0.0008828783,0.3014179,0.001218032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861346,0.0001570149,0.002583847,0.001356642,0.008953322,0.0005271753,0.000005231417,0.00003728065,0.0002448246],"genre_scores_gemma":[0.9950081,0.000258337,0.003519976,0.0001661127,0.0005033861,0.00005495233,0.0002032957,0.00002507953,0.0002608173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4437346,"threshold_uncertainty_score":0.4924952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007673204585006591,"score_gpt":0.2195392166365356,"score_spread":0.211866012051529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}