{"id":"W2018193192","doi":"10.3389/fmicb.2014.00381","title":"Production of a recombinant vaccine candidate against Burkholderia pseudomallei exploiting the bacterial N-glycosylation machinery","year":2014,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Glycoconjugate; Glycan; Glycosylation; Microbiology; Glycoprotein; Burkholderia pseudomallei; Biology; Immune system; Escherichia coli; Bacteria; Biochemistry; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001841763,0.0003273839,0.0002340528,0.0001543294,0.00009238122,0.0002717867,0.0001705189,0.000280281,0.0005284681],"category_scores_gemma":[0.0001709791,0.000103664,0.0001978302,0.0001865213,0.0001152696,0.0001992249,0.0001861615,0.0004616752,0.0003235879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994494,"about_ca_system_score_gemma":0.000168803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256006,"about_ca_topic_score_gemma":0.0004343391,"domain_scores_codex":[0.9998901,0.00002942908,0.00001012257,0.00001792022,0.00002824362,0.00002417939],"domain_scores_gemma":[0.9999228,0.00001204905,0.00002357261,0.00001160676,0.00001205575,0.00001791638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002968106,0.00001831019,0.0001292999,0.00002094453,0.000002318378,0.00003589899,0.000006399897,0.00008819725,0.9986115,0.00005534259,0.00001566705,0.0009864693],"study_design_scores_gemma":[0.00001986498,0.000422413,0.001272071,0.000007518499,0.00001592397,0.0002620354,0.00002496143,0.001018116,0.9933668,0.00004579042,0.003540234,0.000004264781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822738,0.001139162,0.01493225,0.0001848442,0.00004863585,0.0001066471,0.0002953496,0.00007415756,0.00094521],"genre_scores_gemma":[0.977028,0.0008446255,0.01865355,0.00006633205,0.00001380599,0.00004214497,0.0009109576,0.00002356825,0.002416874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005284681,"threshold_uncertainty_score":0.001767874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007673204585006591,"score_gpt":0.2195392166365356,"score_spread":0.211866012051529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}