{"id":"W2018196746","doi":"10.1038/sj.gt.3302932","title":"Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Science Council","keywords":"Medulloblastoma; Cytosine deaminase; Neural stem cell; Cancer research; Glioma; Biology; Systemic administration; Stem cell; Genetic enhancement; In vivo; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002213254,0.00034749,0.000272932,0.0001679567,0.0003801667,0.00009186445,0.0003461276,0.00007161861,0.0001259127],"category_scores_gemma":[0.000002881085,0.0003143842,0.00008725146,0.0002620979,0.00009121047,0.000114124,0.0001251655,0.0001447959,0.00005801524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000380301,"about_ca_system_score_gemma":0.00001309305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006168393,"about_ca_topic_score_gemma":0.000001849452,"domain_scores_codex":[0.9976392,0.000164685,0.0003232987,0.0007629558,0.0004478105,0.0006620547],"domain_scores_gemma":[0.9991274,0.0001055411,0.00009181442,0.0003303681,0.00001823441,0.0003266575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002193698,0.0001495908,0.00005197179,0.000002061644,0.000008083122,0.0001126763,0.0005426835,0.00007429536,0.9954715,0.0001589234,0.00004044658,0.003168364],"study_design_scores_gemma":[0.0008775659,0.001361474,0.0006672886,0.000002805379,0.000005181577,0.0001057498,0.00006660811,0.000173059,0.9952837,0.0000151939,0.001121769,0.0003195982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975432,0.0003542339,0.0007321433,0.00007205922,0.0005892476,0.0004830083,0.00001579586,0.0001528627,0.00005752222],"genre_scores_gemma":[0.9940544,0.00005880352,0.0003631304,0.005041644,0.0001846114,0.00002223293,6.242933e-7,0.0000817137,0.0001928713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004969585,"threshold_uncertainty_score":0.9999308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04711239520690628,"score_gpt":0.2882207735763834,"score_spread":0.2411083783694771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}