{"id":"W2018196746","doi":"10.1038/sj.gt.3302932","title":"Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma","year":2007,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Science Council","keywords":"Medulloblastoma; Cytosine deaminase; Neural stem cell; Cancer research; Glioma; Biology; Systemic administration; Stem cell; Genetic enhancement; In vivo; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004638855,0.0003521818,0.0004266988,0.0008272585,0.0003597298,0.0003516895,0.0003294186,0.0004903493,0.002799947],"category_scores_gemma":[0.0002720143,0.0002220752,0.0003713013,0.0003747892,0.0006484635,0.0003489133,0.0002478411,0.0008822494,0.0004149691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005839487,"about_ca_system_score_gemma":0.0006779989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003435411,"about_ca_topic_score_gemma":0.003972339,"domain_scores_codex":[0.9996971,0.00004378955,0.00002917633,0.00006117596,0.00008149412,0.00008726649],"domain_scores_gemma":[0.9998648,0.0000592146,0.00002082318,0.00002376851,0.00001139222,0.00001985308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007097272,0.0005177591,0.0004406874,0.0001487083,0.00003450034,0.0004816827,0.0002213025,0.0007408774,0.9871737,0.002486544,0.0003289474,0.006715591],"study_design_scores_gemma":[0.0001045915,0.0007143641,0.00053763,0.000005295492,0.00003851273,0.0002063101,0.00004682743,0.001039663,0.9943251,0.000135147,0.002843322,0.000003319674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875599,0.001221151,0.006112082,0.0001982552,0.0001404134,0.0003164908,0.0003916725,0.0001369506,0.00392308],"genre_scores_gemma":[0.9898707,0.001020656,0.004277212,0.00004601877,0.00002358476,0.0001658357,0.0003427065,0.00003733308,0.004215996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003435411,"threshold_uncertainty_score":0.00936681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04711239520690628,"score_gpt":0.2882207735763834,"score_spread":0.2411083783694771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}