{"id":"W2018201647","doi":"10.1007/s40265-014-0293-6","title":"Antiepileptic Drugs for the Treatment of Agitation and Aggression in Dementia: Do They Have a Place in Therapy?","year":2014,"lang":"en","type":"review","venue":"Drugs","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"H. Lundbeck A/S; Pfizer","keywords":"Oxcarbazepine; Tolerability; Medicine; Levetiracetam; Topiramate; Dementia; Gabapentin; Lamotrigine; Psychiatry; Observational study; Aggression; Vigabatrin; Carbamazepine; Donepezil; Intensive care medicine; Adverse effect; Anticonvulsant; Epilepsy; Pharmacology; Alternative medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004185296,0.0002386726,0.001191015,0.0001245884,0.00004498573,0.00001118716,0.00006027363,0.000119511,0.000006587764],"category_scores_gemma":[0.00009949771,0.0001081796,0.0001935208,0.00007403662,0.00006525454,0.00001890467,0.00002253218,0.0001170808,0.000001514109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008365385,"about_ca_system_score_gemma":0.00003997557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005828119,"about_ca_topic_score_gemma":0.00002351788,"domain_scores_codex":[0.9989093,0.0001683831,0.0003779135,0.0002429367,0.0001270613,0.0001743816],"domain_scores_gemma":[0.9979555,0.001589406,0.000238861,0.0001365144,0.00004648488,0.00003321491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001242105,0.0003293223,0.0001077039,0.003076712,0.0002669759,0.000003493901,0.002458983,0.000001289132,0.000005255244,0.00001578338,0.0001538379,0.9934564],"study_design_scores_gemma":[0.006812686,0.001894502,0.0003513473,0.02440388,0.001420485,0.00000387623,0.000564367,0.0002820621,0.0000330698,0.0001656749,0.9638374,0.0002306372],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008414926,0.9881052,0.000005376889,0.0003093437,0.00007727682,0.002929637,0.00001574836,0.000007560356,0.0001349623],"genre_scores_gemma":[0.0231696,0.9759151,0.00003143022,0.0001441512,0.0000711615,0.0005755239,0.00002287191,0.00001661032,0.00005348748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9932258,"threshold_uncertainty_score":0.4411438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05138615566476509,"score_gpt":0.3946525175362661,"score_spread":0.3432663618715011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}