{"id":"W2018237098","doi":"10.1038/nrc2869","title":"Cartilage tumours and bone development: molecular pathology and possible therapeutic targets","year":2010,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Bone Tumor Diagnosis and Treatments","field":"Medicine","cited_by":272,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto; SickKids Foundation; Mount Sinai Hospital","funders":"","keywords":"Chondrosarcoma; Cancer research; Hedgehog signaling pathway; Cartilage; Hedgehog; Pathology; Biology; Medicine; Signal transduction; Anatomy; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006730648,0.001214235,0.001833128,0.002189593,0.0003389084,0.001218427,0.001243953,0.001629899,0.003848115],"category_scores_gemma":[0.0006410137,0.0004424846,0.000460912,0.002664767,0.0009621049,0.001612003,0.0008705603,0.002505805,0.003338152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009877002,"about_ca_system_score_gemma":0.001081987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287307,"about_ca_topic_score_gemma":0.003158353,"domain_scores_codex":[0.999782,0.00003349108,0.00002532588,0.0000300617,0.0001045244,0.00002460782],"domain_scores_gemma":[0.9996185,0.0001612043,0.00004599694,0.00001337869,0.0001167981,0.00004411181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001003409,0.00009349634,0.0001535339,0.009656355,0.00007304078,0.0004034135,0.00004823338,0.0005644148,0.005473897,0.005341424,0.06534396,0.9127479],"study_design_scores_gemma":[0.00002737658,0.00005752736,0.0007204553,0.001680661,0.0000577837,0.002344619,0.00006607343,0.00009081476,0.0006704212,0.002751468,0.9915128,0.00002001634],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005480115,0.9985855,0.000119308,0.0003290114,0.0002166233,0.000002939136,0.0000102824,0.000005617623,0.0006759296],"genre_scores_gemma":[0.0003499862,0.9986872,0.0001231397,0.000138304,0.000170285,0.000004531808,0.00001749363,8.269242e-7,0.0005082195],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003848115,"threshold_uncertainty_score":0.01287317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02550217506779571,"score_gpt":0.3558541349164441,"score_spread":0.3303519598486483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}